Infection by protozoan parasites of the genus Leishmania results in the development of
leishmaniasis, an increasingly prevalent group of diseases affecting over 12 million people …

MicroRNAs (miRNAs) are critical mediators of posttranscriptional regulation via their
targeting of the imperfect antisense complementary regions of coding and non-coding …

Leishmania are protozoan parasites that predominantly reside in myeloid cells within their
mammalian hosts. Monocytes and macrophages play a central role in the pathogenesis of …

For a long time Leishmaniasis had been considered as a neglected tropical disease.
Recently, it has become a priority in public health all over the world for different aspects such …

Leishmania RNA virus (LRV) is an important virulence factor associated with the
development of mucocutaneous Leishmaniasis, a severe form of the disease. LRV-mediated …

Sepsis is a clinical syndrome defined as a dysregulated host response to infection resulting
in life-threatening organ dysfunction. Sepsis is a major public health concern associated …

The presence of the endogenous Leishmania RNA virus 1 (LRV1) replicating stably within
some parasite species has been associated with the development of more severe forms of …

Knowledge of viral diversity is expanding greatly, but many lineages remain underexplored.
We surveyed RNA viruses in 52 cultured monoxenous relatives of the human parasite …

Infections caused by protozoan parasites burden the world with huge costs in terms of
human and animal health. Most parasitic diseases caused by protozoans are neglected …

Background Trypanosomatids are parasitic flagellates well known because of some
representatives infecting humans, domestic animals, and cultural plants. Many …