MicroRNAs (miRNAs) are a class of non-coding RNAs involved in post-transcriptional gene
silencing. A small number of striated muscle-specific miRNAs have been identified and …

There is an urgent unmet need for robust and reliable biomarkers for early diagnosis,
prognosis, and prediction of response to specific treatments of many aggressive and deadly …

Background—Chronic heart failure is characterized by left ventricular remodeling and
reactivation of a fetal gene program; the underlying mechanisms are only partly understood …

Skeletal myoblast fusion in vitro requires the expression of connexin43 (Cx43) gap junction
channels. However, gap junctions are rapidly downregulated after the initiation of myoblast …

Objective To use an in vitro model of chondrogenesis to identify microRNAs (miRNAs) with a
functional role in cartilage homeostasis. Methods The expression of miRNAs was measured …

The expression of three microRNAs, miR-1, miR-206 and miR-133 is restricted to skeletal
myoblasts and cardiac tissue during embryo development and muscle cell differentiation …

The major endocannabinoid (eCB) 2-arachidonoylglycerol (2-AG) is a member of the
endocannabinoid system (ECS) that participates in cell proliferation and apoptosis …

Members of the Slit family of secreted ligands interact with Roundabout (Robo) receptors to
provide guidance cues for many cell types. For example, Slit/Robo signaling elicits repulsion …

Rationale: Establishment of a functional vasculature requires the interconnection and
remodeling of nascent blood vessels. Precise regulation of factors that influence endothelial …

miRNAs are small RNAs directing many developmental processes by posttranscriptional
regulation of protein-coding genes. We uncovered a new role for miR-1-1/133a-2 and miR-1 …