Oxidative stress and inflammation in diabetic nephropathy: role of polyphenols

Q Jin, T Liu, Y Qiao, D Liu, L Yang, H Mao… - Frontiers in …, 2023 - frontiersin.org
Diabetic nephropathy (DN) often leads to end-stage renal disease. Oxidative stress
demonstrates a crucial act in the onset and progression of DN, which triggers various …

Toxicity of advanced glycation end products

A Kuzan - Biomedical Reports, 2021 - spandidos-publications.com
Advanced glycation end‑products (AGEs) are proteins or lipids glycated nonenzymatically
by glucose, or other reducing sugars and their derivatives, such as glyceraldehyde …

[HTML][HTML] The potential health benefits of gallic acid: Therapeutic and food applications

M Hadidi, R Liñán-Atero, M Tarahi, MC Christodoulou… - Antioxidants, 2024 - mdpi.com
Gallic acid (GA), a phenolic acid found in fruits and vegetables, has been consumed by
humans for centuries. Its extensive health benefits, such as antimicrobial, antioxidant …

Diabetic nephropathy: significance of determining oxidative stress and opportunities for antioxidant therapies

M Darenskaya, S Kolesnikov, N Semenova… - International Journal of …, 2023 - mdpi.com
Diabetes mellitus (DM) belongs to the category of socially significant diseases with epidemic
rates of increases in prevalence. Diabetic nephropathy (DN) is a specific kind of kidney …

Dietary gallic acid as an antioxidant: A review of its food industry applications, health benefits, bioavailability, nano-delivery systems, and drug interactions

Z Xiang, H Guan, X Zhao, Q Xie, Z Xie, F Cai… - Food Research …, 2024 - Elsevier
Gallic acid (GA), a dietary phenolic acid with potent antioxidant activity, is widely distributed
in edible plants. GA has been applied in the food industry as an antimicrobial agent, food …

Polyphenols and their metabolites in renal diseases: An overview

Í Guerreiro, C Ferreira-Pêgo, D Carregosa, CN Santos… - Foods, 2022 - mdpi.com
Kidney diseases constitute a worldwide public health problem, contributing to morbidity and
mortality. The present study aimed to provide an overview of the published data regarding …

Natural compounds regulate the PI3K/Akt/GSK3β pathway in myocardial ischemia-reperfusion injury

AH Ajzashokouhi, R Rezaee, N Omidkhoda, G Karimi - Cell Cycle, 2023 - Taylor & Francis
ABSTRACT The PI3K/Akt/GSK3β pathway is crucial in regulating cardiomyocyte growth and
survival. It has been shown that activation of this pathway alleviates the negative impact of …

Pristine, carboxylated, and hybrid multi-walled carbon nanotubes exert potent antioxidant activities in in vitro-cell free systems

P Vardakas, IA Kartsonakis, ID Kyriazis… - Environmental …, 2023 - Elsevier
Multi-walled carbon nanotubes (MWCNTs) are tubular-shaped carbon allotropes, composed
of multiple concentric graphene cylinders. The extended systems of conjugated double …

[HTML][HTML] Toxicity of Dithiothreitol (DTT) to Drosophila melanogaster

Y Wang, M Misto, J Yang, N Gehring, X Yu… - Toxicology Reports, 2021 - Elsevier
The thiol-containing compound Dithiothreitol (DTT) has been shown to be toxic to cultured
cells by inducing the generation of reactive oxygen species that ultimately cause cell death …

Syzygium cumini (L.) skeels mitigate diabetic nephropathy by regulating Nrf2 pathway and mitocyhondrial dysfunction: In vitro and in vivo studies

NS Bangar, A Dixit, MM Apte, RS Tupe - Journal of Ethnopharmacology, 2025 - Elsevier
Ethnopharmacological prevalence Hyperglycemia in diabetes increases the generation of
advanced glycation end products (AGEs) through non-enzymatic reactions. The interaction …