Liquid biopsy in colorectal cancer

S Najafi, J Majidpoor, K Mortezaee - Clinica Chimica Acta, 2024 - Elsevier
Liquid biopsy refers to a set of pathological samples retrieved from non-solid sources, such
as blood, cerebrospinal fluid, urine, and saliva through non-invasive or minimally invasive …

Benchtop technologies for circulating tumor cells separation based on biophysical properties

WS Low, WAB Wan Abas - BioMed research international, 2015 - Wiley Online Library
Circulating tumor cells (CTCs) are tumor cells that have detached from primary tumor site
and are transported via the circulation system. The importance of CTCs as prognostic …

Detection and recovery of circulating colon cancer cells using a dielectrophoresis-based device: KRAS mutation status in pure CTCs

F Fabbri, S Carloni, W Zoli, P Ulivi, G Gallerani, P Fici… - Cancer letters, 2013 - Elsevier
The characterization of circulating tumor cells (CTCs) could substantially improve the
management of cancer patients. However, their study is still a matter of debate, often due to …

Molecular characterization of circulating tumor cells in human metastatic colorectal cancer

J Barbazan, L Alonso-Alconada, L Muinelo-Romay… - PloS one, 2012 - journals.plos.org
Metastatic colorectal cancer (mCRC) relies on the detachment of aggressive malignant cells
from the primary tumor into the bloodstream and, concordantly, the presence of these …

Screening for colorectal cancer: established and emerging modalities

N Pawa, T Arulampalam, JD Norton - Nature reviews Gastroenterology …, 2011 - nature.com
It has been estimated that> 95% of cases of colorectal cancer (CRC) would benefit from
curative surgery if diagnosis was made at an early or premalignant polyp stage of disease …

Detection of cancer cells in the cerebrospinal fluid: current methods and future directions

CL Weston, MJ Glantz, JR Connor - Fluids and Barriers of the CNS, 2011 - Springer
The spread of cancer into the central nervous system is a serious problem leading to
neurological symptoms and rapid mortality. The current tools available for detecting the …

[HTML][HTML] Identification and enumeration of circulating tumor cells in the cerebrospinal fluid of breast cancer patients with central nervous system metastases

AS Patel, JE Allen, DT Dicker, KL Peters, JM Sheehan… - Oncotarget, 2011 - ncbi.nlm.nih.gov
The number of circulating tumor cells (CTCs) in the peripheral blood of metastatic breast
cancer patients is now an established prognostic marker. While the central nervous system …

[HTML][HTML] Circulating tumor cells in clinical research and monitoring patients with colorectal cancer

C Burz, VV Pop, R Buiga, S Daniel, G Samasca… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Colorectal cancer remains a frequent disease to which screening and target therapy exist,
but despite this is still marked by a high mortality rate. Even though radical surgery may be …

Markers of circulating tumour cells in the peripheral blood of patients with melanoma correlate with disease recurrence and progression

AL Reid, M Millward, R Pearce, M Lee… - British Journal of …, 2013 - academic.oup.com
Background Multimarker quantitative real‐time polymerase chain reaction (qRT‐PCR)
represents an effective method for detecting circulating tumour cells in the peripheral blood …

Prognostic value of putative circulating cancer stem cells in patients undergoing hepatic resection for colorectal liver metastasis

P Pilati, S Mocellin, L Bertazza, F Galdi… - Annals of surgical …, 2012 - Springer
Background Although surgery is the gold standard treatment of hepatic metastasis from
colorectal cancer (CRC), many patients ultimately die of their disease. We tested the …