Tuft cells are found in tissues with distinct stem cell compartments, tissue architecture, and
luminal exposures but converge on a shared transcriptional program, including expression …

Rapid reaction to microbes invading mucosal tissues is key to protect the host against
disease. Respiratory tissue‐resident memory T (TRM) cells provide superior immunity …

The olfactory neuroepithelium serves as a sensory organ for odors and forms part of the
nasal mucosal barrier. Olfactory sensory neurons are surrounded and supported by …

Severe viral pneumonia can induce rapid expansion of KRT5+ basal-like cells in small
airways and alveoli; this forms a scar-like structure that persists in the injured alveoli and …

Current treatment guidelines refer to small cell lung cancer (SCLC), one of the deadliest
human malignancies, as a homogeneous disease. Accordingly, SCLC therapy comprises …

Tuft cells are a rare and morphologically distinct chemosensory cell type found throughout
many organs, including the gastrointestinal tract. These cells were identified by their unique …

Recognizing that enteric tuft cells can signal the presence of nematode parasites, we
investigated whether tuft cells are required for the expulsion of the cestode, Hymenolepis …

During recent years chemosensory cells in extraoral tissues have been established as
mediators for the detection and regulation of innate immune processes in response to …

The persistent murine norovirus strain MNVCR6 is a model for human norovirus and enteric
viral persistence. MNVCR6 causes chronic infection by directly infecting intestinal tuft cells …

Multiomic profiling of single cells by sequencing is a powerful technique for investigating
cellular diversity. Existing droplet-based microfluidic methods produce many cell-free …