Biological diversity of prokaryotic type IV secretion systems

CE Alvarez-Martinez, PJ Christie - Microbiology and Molecular …, 2009 - Am Soc Microbiol
Type IV secretion systems (T4SS) translocate DNA and protein substrates across prokaryotic
cell envelopes generally by a mechanism requiring direct contact with a target cell. Three …

Conjugation in gram‐positive bacteria

N Goessweiner-Mohr, K Arends… - … : Biology and Impact …, 2015 - Wiley Online Library
Conjugative transfer is an important driver in evolution, enabling bacteria to acquire new
traits (1, 2, 3, 4, 5). During conjugative transfer, DNA translocation across the cell envelopes …

Conjugative type IV secretion systems in Gram-positive bacteria

N Goessweiner-Mohr, K Arends, W Keller, E Grohmann - Plasmid, 2013 - Elsevier
Bacterial conjugation presents the most important means to spread antibiotic resistance and
virulence factors among closely and distantly related bacteria. Conjugative plasmids are the …

Broad-host-range Inc18 plasmids: occurrence, spread and transfer mechanisms

V Kohler, A Vaishampayan, E Grohmann - Plasmid, 2018 - Elsevier
Conjugative plasmid transfer is one of the major mechanisms responsible for the spread of
antibiotic resistance and virulence genes. The incompatibility (Inc) 18 group of plasmids is a …

A type IV-secretion-like system is required for conjugative DNA transport of broad-host-range plasmid pIP501 in gram-positive bacteria

MY Abajy, J Kopec, K Schiwon, M Burzynski… - Journal of …, 2007 - Am Soc Microbiol
Plasmid pIP501 has a very broad host range for conjugative transfer among a wide variety of
gram-positive bacteria and gram-negative Escherichia coli. Functionality of the pIP501 …

The Tcp conjugation system of Clostridium perfringens

JA Wisniewski, JI Rood - Plasmid, 2017 - Elsevier
Abstract The Gram-positive pathogen Clostridium perfringens possesses a family of large
conjugative plasmids that is typified by the tetracycline resistance plasmid pCW3. Since …

TraG encoded by the pIP501 type IV secretion system is a two-domain peptidoglycan-degrading enzyme essential for conjugative transfer

K Arends, EK Celik, I Probst… - Journal of …, 2013 - Am Soc Microbiol
ABSTRACT pIP501 is a conjugative broad-host-range plasmid frequently present in
nosocomial Enterococcus faecalis and Enterococcus faecium isolates. We focus here on the …

The 2.5 Å structure of the enterococcus conjugation protein TraM resembles VirB8 type IV secretion proteins

N Goessweiner-Mohr, L Grumet, K Arends… - Journal of Biological …, 2013 - ASBMB
Conjugative plasmid transfer is the most important means of spreading antibiotic resistance
and virulence genes among bacteria and therefore presents a serious threat to human …

TcpM: a novel relaxase that mediates transfer of large conjugative plasmids from Clostridium perfringens

JA Wisniewski, DA Traore, TL Bannam… - Molecular …, 2016 - Wiley Online Library
Conjugative transfer of toxin and antibiotic resistance plasmids in C lostridium perfringens is
mediated by the tcp conjugation locus. Surprisingly, neither a relaxase gene nor an origin of …

Specificity determinants of conjugative DNA processing in the Enterococcus faecalis plasmid pCF10 and the Lactococcus lactis plasmid pRS01

Y Chen, JH Staddon, GM Dunny - Molecular microbiology, 2007 - Wiley Online Library
The DNA‐processing region of the Enterococcus faecalis pheromone‐responsive plasmid
pCF10 is highly similar to that of the otherwise unrelated plasmid pRS01 from Lactococcus …