[HTML][HTML] Versatile signaling mechanisms of inositol pyrophosphates

MN Trung, D Furkert, D Fiedler - Current opinion in chemical biology, 2022 - Elsevier
Inositol pyrophosphates (PP-InsPs) constitute a group of highly charged messengers, which
regulate central biological processes in health and disease, such as cellular phosphate and …

Functions, Mechanisms, and therapeutic applications of the inositol pyrophosphates 5PP-InsP5 and InsP8 in mammalian cells

J Qi, L Shi, L Zhu, Y Chen, H Zhu, W Cheng… - Journal of …, 2024 - Springer
Water-soluble myo-inositol phosphates have long been characterized as second
messengers. The signaling properties of these compounds are determined by the number …

Label-free imaging and biomarker analysis of exosomes with plasmonic scattering microscopy

P Zhang, J Jiang, X Zhou, J Kolay, R Wang, Z Wan… - Chemical …, 2022 - pubs.rsc.org
Exosome analysis is a promising tool for clinical and biological research applications.
However, detection and biomarker quantification of exosomes is technically challenging …

Inositol pyrophosphate catabolism by three families of phosphatases regulates plant growth and development

F Laurent, SM Bartsch, A Shukla, F Rico-Resendiz… - PLoS …, 2024 - journals.plos.org
Inositol pyrophosphates (PP-InsPs) are nutrient messengers whose cellular levels are
precisely regulated. Diphosphoinositol pentakisphosphate kinases (PPIP5Ks) generate the …

Metabolism and functions of inositol pyrophosphates: insights gained from the application of synthetic analogues

SB Shears, H Wang - Molecules, 2020 - mdpi.com
Inositol pyrophosphates (PP-InsPs) comprise an important group of intracellular, diffusible
cellular signals that a wide range of biological processes throughout the yeast, plant, and …

Chemical tools to investigate inositol pyrophosphate protein interactions

D Furkert - 2023 - edoc.hu-berlin.de
Inositol pyrophosphates (PP-InsPs) are a ubiquitous group of highly phosphorylated
eukaryotic messengers. They have been linked to a panoply of central cellular processes …

A small signaling domain controls PPIP5K phosphatase activity in phosphate homeostasis

P Raia, K Lee, SM Bartsch, F Rico-Resendiz… - bioRxiv, 2024 - biorxiv.org
Inositol pyrophosphates (PP-InsPs) are highly phosphorylated nutrient messengers. The
final step of their biosynthesis is catalyzed by diphosphoinositol pentakisphosphate kinase …

[PDF][PDF] A GAF domain mediates inositol pyrophosphate substrate channeling in PPIP5K phosphatases.(89

P Raia, K Lee, SM Bartsch, F Rico-Resendiz, D Fiedler… - biorxiv.org
Inositol pyrophosphates are highly phosphorylated nutrient messengers. The final step of
their biosynthesis is catalyzed by diphosphoinositol pentakisphosphate kinase (PPIP5K) …