Propofol is an intravenous hypnotic drug that is used for induction and maintenance of
sedation and general anaesthesia. It exerts its effects through potentiation of the inhibitory …

Allergists and clinical immunologists around the world are increasingly faced with the task of
addressing drug allergy and hypersensitivity due to the increase in drug reactions …

Background Anaphylaxis during anaesthesia is a serious complication for patients and
anaesthetists. Methods The 6th National Audit Project (NAP6) on perioperative anaphylaxis …

Perioperative immediate hypersensitivity reactions are rare. Subsequent allergy
investigation is complicated by multiple simultaneous drug exposures, the use of drugs with …

Suspected perioperative hypersensitivity reactions are rare but contribute significantly to the
morbidity and mortality of surgical procedures. Recent publications have highlighted the …

This guideline advises on the management of patients with egg allergy. Most commonly egg
allergy presents in infancy, with a prevalence of approximately 2% in children and 0.1% in …

Anaphylaxis is an acute, life-threatening, multisystem syndrome resulting from the sudden
release of mediators by mast cells and basophils. Although anaphylaxis is often under …

Propofol is an intravenous short‐acting anesthetic widely used to induce and maintain
general anesthesia and to provide procedural sedation. The potential for propofol …

Perioperative hypersensitivity reactions constitute a first-line problem for anesthesiologists
and allergists. Therefore, hospitals should have a consensus protocol for the diagnosis and …

Key points Anaphylactic reactions may be either of immune (allergy, usually IgE-mediated,
sometimes IgG-mediated) or non-immune origin. The incidence of anaphylactic reactions …