Cancer-associated fibroblasts in intrahepatic cholangiocarcinoma: Insights into origins, heterogeneity, lymphangiogenesis, and peritoneal metastasis

S Affὸ, L Sererols-Viñas, G Garcia-Vicién… - The American Journal of …, 2024 - Elsevier
Intrahepatic cholangiocarcinoma (iCCA) denotes a rare, highly malignant and
heterogeneous class of primary liver adenocarcinomas exhibiting phenotypic characteristics …

Matricellular proteins in intrahepatic cholangiocarcinoma

AE Sirica - Advances in Cancer Research, 2022 - Elsevier
Intrahepatic cholangiocarcinoma (iCCA) is typically characterized by a prominent
desmoplastic stroma that is often the most dominant feature of the tumor. This tumor reactive …

Modelling metastatic colonization of cholangiocarcinoma organoids in decellularized lung and lymph nodes

GS van Tienderen, MEA van Beek, IJ Schurink… - Frontiers in …, 2023 - frontiersin.org
Cholangiocarcinoma (CCA) is a type of liver cancer with an aggressive phenotype and
dismal outcome in patients. The metastasis of CCA cancer cells to distant organs, commonly …

[HTML][HTML] β-Eudesmol inhibits the migration of cholangiocarcinoma cells by suppressing epithelial-mesenchymal transition via PI3K/AKT and p38MAPK modulation

B Acharya, W Chaijaroenkul… - Asian Pacific Journal of …, 2022 - ncbi.nlm.nih.gov
Background: Cholangiocarcinoma (CCA) is a highly aggressive tumor with a greater risk of
distant metastasis. A drug that prevents CCA development and spread is urgently needed. In …

Gemcitabine with cisplatin versus hepatic arterial infusion pump chemotherapy for liver-confined unresectable intrahepatic cholangiocarcinoma

S Franssen, JJ Holster, JS Jolissaint… - Annals of surgical …, 2024 - Springer
Background A post-hoc analysis of ABC trials included 34 patients with liver-confined
unresectable intrahepatic cholangiocarcinoma (iCCA) who received systemic chemotherapy …

Bone metastases from intrahepatic cholangiocarcinoma confer worse prognosis

I Garajová, F Gelsomino, M Salati, F Leonardi… - Current …, 2023 - mdpi.com
Background: Metastatic intrahepatic cholangiocarcinoma still has a dismal prognosis. The
aim of our study was to investigate the prognostic role of bone metastases in patients …

Stereotactic radiosurgery for brain metastasis from cholangiocarcinoma

AH Düzkalir, Y Samanci, CC Lee, HC Yang… - Journal of …, 2024 - thejns.org
OBJECTIVE Accounting for approximately 15% of primary liver cancers and 3% of
gastrointestinal malignancies, cholangiocarcinoma (CCA) poses a serious health concern …

Diffusion-weighted imaging as an imaging biomarker for assessing survival of patients with intrahepatic mass-forming cholangiocarcinoma

J Promsorn, K Eurboonyanun, P Chadbunchachai… - Abdominal …, 2022 - Springer
Background Mass-forming cholangiocarcinoma is the most common form of intrahepatic
cholangiocarcinoma and is associated with a worse prognosis. This study aimed to assess …

Establishment and external validation of prognosis prediction nomogram for patients with distant metastatic intrahepatic cholangiocarcinoma: based on a large …

C Yuan, S Zou, K Wang, Z Hu - BMC cancer, 2024 - Springer
Background Most patients with intrahepatic cholangiocarcinoma (ICC) have developed
distant metastasis at the time of diagnosis, while there is rear related nomogram to predict …

Standardized reporting of intrahepatic cholangiocarcinoma

AS Kierans, GM Cunha, MJ King, RM Marks… - Abdominal …, 2024 - Springer
Abdominal Radiology https://doi. org/10.1007/s00261-024-04582-4 in a separate article in
this special edition on cholangiocarcinoma imaging. iCCA is an aggressive tumor with a …