Hemodialysis, the most common modality of renal replacement therapy, is critically required
to remove uremic toxins from the blood of patients with end-stage kidney disease. However …

Continuous blood purification technology such as hemodiafiltration has been used
worldwide for saving patients suffering from severe diseases or organ function failure …

In recent years, dopamine has stood out as an all-round talent in the field of membrane
modification. Membranes post-modified with polydopamine or made out of materials pre …

Polyethyleneimine-coated polyacrylonitrile (AN69ST) and polymethyl methacrylate (PMMA)
membranes are effective cytokine-adsorbing hemofilters; however, the cytokine-adsorption …

Severe vascular calcification develops almost invariably in chronic kidney patients posing a
substantial risk to quality of life and survival. This unmet medical need demands …

Since the first attempt at extracorporeal renal replacement therapy, renal replacement
therapy has been constantly improved. In the field of hemodialysis, substantial efforts have …

Introduction The low incidence of intradialytic hypotension (IDH) in high-volume (HV)
hemodiafiltration (HDF) may help in maintaining gut perfusion during treatment …

The high mobility group box 1 protein (HMGB1) is recognized as a prototypical endogenous
danger cytokine in sepsis. We previously reported that a polyacrylonitrile (AN69ST) …

Objective: In intensive care medicine, continuous renal replacement therapy (CRRT) is
important for critically ill patients. Various types of dialysis membranes are currently used in …

Large middle molecules (LMM) are an important subclass of uremic toxins. Many of them
have been linked with poor outcomes in hemodialysis (HD) patients. The onset of high-flux …