Enhancing the therapeutic efficacy of nanoparticles for cancer treatment using versatile targeted strategies

H Tian, T Zhang, S Qin, Z Huang, L Zhou, J Shi… - Journal of hematology & …, 2022 - Springer
Poor targeting of therapeutics leading to severe adverse effects on normal tissues is
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …

Advanced nitric oxide generating nanomedicine for therapeutic applications

Z Wang, A Jin, Z Yang, W Huang - ACS nano, 2023 - ACS Publications
Nitric oxide (NO), a gaseous transmitter extensively present in the human body, regulates
vascular relaxation, immune response, inflammation, neurotransmission, and other crucial …

Multiple stimuli‐responsive nanozyme‐based cryogels with controlled NO release as self‐adaptive wound dressing for infected wound healing

Y Yang, M Li, G Pan, J Chen… - Advanced Functional …, 2023 - Wiley Online Library
Wound with drug‐resistant bacterial infections has become a serious challenge for the
healthcare system, and designing wound dressing to self‐adapt to the need of different …

Current and promising applications of Hf (IV)-based MOFs in clinical cancer therapy

X Chen, M Li, M Lin, C Lu, A Kumar, Y Pan… - Journal of Materials …, 2023 - pubs.rsc.org
Cancer is one of the greatest challenges in medical science today as it poses a serious
threat to human life. In view of this, myriad of therapeutic strategies are being developed for …

Manipulating intratumoral fenton chemistry for enhanced chemodynamic and chemodynamic‐synergized multimodal therapy

Y Zhou, S Fan, L Feng, X Huang, X Chen - Advanced Materials, 2021 - Wiley Online Library
Chemodynamic therapy (CDT) uses the tumor microenvironment‐assisted intratumoral
Fenton reaction for generating highly toxic hydroxyl free radicals (• OH) to achieve selective …

Gas therapy potentiates aggregation-induced emission luminogen-based photoimmunotherapy of poorly immunogenic tumors through cGAS-STING pathway …

K Wang, Y Li, X Wang, Z Zhang, L Cao, X Fan… - Nature …, 2023 - nature.com
The immunologically “cold” microenvironment of triple negative breast cancer results in
resistance to current immunotherapy. Here, we reveal the immunoadjuvant property of gas …

The recent progress on metal–organic frameworks for phototherapy

Q Zheng, X Liu, Y Zheng, KWK Yeung, Z Cui… - Chemical Society …, 2021 - pubs.rsc.org
Some infectious or malignant diseases such as cancers are seriously threatening the health
of human beings all over the world. The commonly used antibiotic therapy cannot effectively …

Photodynamic therapy: Innovative approaches for antibacterial and anticancer treatments

M Kolarikova, B Hosikova, H Dilenko… - Medicinal Research …, 2023 - Wiley Online Library
Photodynamic therapy is an alternative treatment mainly for cancer but also for bacterial
infections. This treatment dates back to 1900 when a German medical school graduate …

Near-infrared light-triggered nitric-oxide-enhanced photodynamic therapy and low-temperature photothermal therapy for biofilm elimination

Z Yuan, C Lin, Y He, B Tao, M Chen, J Zhang, P Liu… - ACS …, 2020 - ACS Publications
Photothermal treatment (PTT) involving a combination of therapeutic modalities recently
emerged as an efficient alternative for combating biofilm. However, PTT-related local high …

Metal-organic frameworks for stimuli-responsive drug delivery

Y Wang, J Yan, N Wen, H Xiong, S Cai, Q He, Y Hu… - Biomaterials, 2020 - Elsevier
Abstract Metal-organic framework (MOF), a novel hybrid porous material which is
composited by metal ions and organic linkers, has drawn increasing attention and became a …