DNA polymerase ζ in DNA replication and repair

SK Martin, RD Wood - Nucleic acids research, 2019 - academic.oup.com
Here, we survey the diverse functions of DNA polymerase ζ (pol ζ) in eukaryotes. In
mammalian cells, REV3L (3130 residues) is the largest catalytic subunit of the DNA …

DNA damage tolerance in stem cells, ageing, mutagenesis, disease and cancer therapy

B Pilzecker, OA Buoninfante, H Jacobs - Nucleic acids research, 2019 - academic.oup.com
The DNA damage response network guards the stability of the genome from a plethora of
exogenous and endogenous insults. An essential feature of the DNA damage response …

[HTML][HTML] Functional specialization of human salivary glands and origins of proteins intrinsic to human saliva

M Saitou, EA Gaylord, E Xu, AJ May, L Neznanova… - Cell reports, 2020 - cell.com
Salivary proteins are essential for maintaining health in the oral cavity and proximal
digestive tract, and they serve as potential diagnostic markers for monitoring human health …

[HTML][HTML] Moebius syndrome: clinical features, diagnosis, management and early intervention

O Picciolini, M Porro, E Cattaneo, S Castelletti… - Italian journal of …, 2016 - Springer
Background Moebius syndrome (MBS) is rare disease characterized by nonprogressive
congenital uni-or bi-lateral facial (ie VII cranial nerve) and abducens (ie VI cranial nerve) …

Epstein-Barr virus NK and T cell lymphoproliferative disease: report of a 2018 international meeting

JI Cohen, K Iwatsuki, YH Ko, H Kimura… - Leukemia & …, 2020 - Taylor & Francis
Epstein-Barr virus (EBV) normally infects B cells, but in some persons the virus infects T or
NK cells. Infection of B cells can result in infectious mononucleosis, and the virus is …

Moebius Syndrome: an updated review of literature

SA Monawwer, S Ali, R Naeem, SH Ali… - Child Neurology …, 2023 - journals.sagepub.com
Moebius Syndrome, is a rare, non-progressive congenital neuropathological syndrome
characterized primarily by the underdevelopment of the facial (CN VII) and abducens nerve …

[HTML][HTML] Moebius syndrome: what we know so far

SMH Zaidi, IN Syed, U Tahir, T Noor, MS Choudhry - Cureus, 2023 - ncbi.nlm.nih.gov
Moebius syndrome (MBS) is a rare congenital cranial nerve disorder characterized by
unilateral, bilateral symmetrical, or asymmetrical facial (VII) and abducens (VI) nerve palsies …

Congenital facial palsy and emotion processing: The case of Moebius syndrome

E De Stefani, Y Nicolini, M Belluardo… - Genes, Brain and …, 2019 - Wiley Online Library
According to the Darwinian perspective, facial expressions of emotions evolved to quickly
communicate emotional states and would serve adaptive functions that promote social …

The genetics of isolated and syndromic clubfoot

B Sadler, CA Gurnett… - Journal of children's …, 2019 - journals.sagepub.com
Purpose Congenital clubfoot is a serious birth defect that affects nearly 0.1% of all births.
Though there is strong evidence for a genetic basis of isolated clubfoot, aside from a handful …

Filling gaps in translesion DNA synthesis in human cells

A Quinet, LK Lerner, DJ Martins, CFM Menck - Mutation Research/Genetic …, 2018 - Elsevier
During DNA replication, forks may encounter unrepaired lesions that hamper DNA
synthesis. Cells have universal strategies to promote damage bypass allowing cells to …