G Storz, J Vogel, KM Wassarman - Molecular cell, 2011 - cell.com
Research on the discovery and characterization of small, regulatory RNAs in bacteria has exploded in recent years. These sRNAs act by base pairing with target mRNAs with which …
E Van Assche, S Van Puyvelde… - Frontiers in …, 2015 - frontiersin.org
Post-transcriptional regulation is a very important mechanism to control gene expression in changing environments. In the past decade, a lot of interest has been directed toward the …
I Caldelari, Y Chao, P Romby… - Cold Spring …, 2013 - perspectivesinmedicine.cshlp.org
Pathogenic bacteria possess intricate regulatory networks that temporally control the production of virulence factors, and enable the bacteria to survive and proliferate after host …
Small non-coding RNAs (sRNAs) are critical post-transcriptional regulators of gene expression. Distinct RNA-binding proteins (RBPs) influence the processing, stability and …
AI Jacob, C Köhrer, BW Davies, UL RajBhandary… - Molecular cell, 2013 - cell.com
Quality control of ribosomes is critical for cellular function since protein mistranslation leads to severe physiological consequences. We report evidence of a previously unrecognized …
P Sobrero, C Valverde - Critical reviews in microbiology, 2012 - Taylor & Francis
Most of the sequenced bacterial genomes contain a gene encoding a protein known as Hfq that resembles the eukaryotic RNA-binding proteins of the LSm family. It was originally …
The RNA chaperone Hfq is a key player in small RNA (sRNA)-mediated regulation of target mRNAs in many bacteria. The absence of this protein causes pleiotropic phenotypes such …
K Arnvig, D Young - RNA biology, 2012 - Taylor & Francis
It is estimated that one third of the human population is infected with Mycobacterium tuberculosis. Efforts to understand the molecular basis of its gene regulation have been …
S Brantl, R Brückner - RNA biology, 2014 - Taylor & Francis
Small regulatory RNAs (sRNAs) that act by base-pairing were first discovered in so-called accessory DNA elements—plasmids, phages, and transposons—where they control …