Small RNAs in bacteria and archaea: who they are, what they do, and how they do it

EGH Wagner, P Romby - Advances in genetics, 2015 - Elsevier
Small RNAs are ubiquitously present regulators in all kingdoms of life. Most bacterial and
archaeal small RNAs (sRNAs) act by antisense mechanisms on multiple target mRNAs …

Regulation by small RNAs in bacteria: expanding frontiers

G Storz, J Vogel, KM Wassarman - Molecular cell, 2011 - cell.com
Research on the discovery and characterization of small, regulatory RNAs in bacteria has
exploded in recent years. These sRNAs act by base pairing with target mRNAs with which …

RNA-binding proteins involved in post-transcriptional regulation in bacteria

E Van Assche, S Van Puyvelde… - Frontiers in …, 2015 - frontiersin.org
Post-transcriptional regulation is a very important mechanism to control gene expression in
changing environments. In the past decade, a lot of interest has been directed toward the …

RNA-mediated regulation in pathogenic bacteria

I Caldelari, Y Chao, P Romby… - Cold Spring …, 2013 - perspectivesinmedicine.cshlp.org
Pathogenic bacteria possess intricate regulatory networks that temporally control the
production of virulence factors, and enable the bacteria to survive and proliferate after host …

RNA-binding proteins driving the regulatory activity of small non-coding RNAs in bacteria

AP Quendera, AF Seixas, RF Dos Santos… - Frontiers in molecular …, 2020 - frontiersin.org
Small non-coding RNAs (sRNAs) are critical post-transcriptional regulators of gene
expression. Distinct RNA-binding proteins (RBPs) influence the processing, stability and …

Conserved bacterial RNase YbeY plays key roles in 70S ribosome quality control and 16S rRNA maturation

AI Jacob, C Köhrer, BW Davies, UL RajBhandary… - Molecular cell, 2013 - cell.com
Quality control of ribosomes is critical for cellular function since protein mistranslation leads
to severe physiological consequences. We report evidence of a previously unrecognized …

The bacterial protein Hfq: much more than a mere RNA-binding factor

P Sobrero, C Valverde - Critical reviews in microbiology, 2012 - Taylor & Francis
Most of the sequenced bacterial genomes contain a gene encoding a protein known as Hfq
that resembles the eukaryotic RNA-binding proteins of the LSm family. It was originally …

Cycling of RNAs on hfq

EGH Wagner - RNA biology, 2013 - Taylor & Francis
The RNA chaperone Hfq is a key player in small RNA (sRNA)-mediated regulation of target
mRNAs in many bacteria. The absence of this protein causes pleiotropic phenotypes such …

Non-coding RNA and its potential role in Mycobacterium tuberculosis pathogenesis

K Arnvig, D Young - RNA biology, 2012 - Taylor & Francis
It is estimated that one third of the human population is infected with Mycobacterium
tuberculosis. Efforts to understand the molecular basis of its gene regulation have been …

Small regulatory RNAs from low-GC Gram-positive bacteria

S Brantl, R Brückner - RNA biology, 2014 - Taylor & Francis
Small regulatory RNAs (sRNAs) that act by base-pairing were first discovered in so-called
accessory DNA elements—plasmids, phages, and transposons—where they control …