Animal models of arthritis are used to better understand pathophysiology of a disease or to
seek potential therapeutic targets or strategies. Focusing on models currently used for …

A common dilemma faced by all animal bioethics committees arises when exceptions are
proposed to the use of analgesics in painful procedures. The committee and researcher …

Complete Freund's adjuvant (CFA) has been used to develop the arthritic or inflammatory
condition in the animal, but there is a lack of information concerning high CFA doses on …

Background The medicinal uses of plants are in many cases based exclusively on traditional
knowledge without enough scientific evidences. Different parts of Moringa oleifera were …

Several studies demonstrated the pharmacological actions of carnosine as well as
hyaluronic acid (HA) during joint inflammation. In that regard, the aim of this study was to …

Rheumatoid arthritis (RA) is of foremost concern among long-term autoimmune disorders, as
it leads to inflammation, exudates, chondral degeneration, and painful joints. Because RA …

Pain has a profound effect on an animal's wellbeing. In Germany, researchers using animals
have been legally required to reduce any possible pain, suffering, distress or lasting harm to …

Anoectochilus roxburghii, a famous Chinese herbal medicine, has been commonly used for
the treatment of liver disease, diabetes, and rheumatoid arthritis. Our study aimed to …

Rheumatoid arthritis (RA) is an autoimmune and chronic inflammatory disease
characterized by joint inflammation. Since the inflammatory condition plays an important role …

Current use of analgesics to control procedure-related pain in laboratory rodents is
unacceptably low. Almost all currently available analgesics were developed in small …