Advanced technological tools to study multidrug resistance in cancer

L Andrei, S Kasas, IO Garrido, T Stanković… - Drug Resistance …, 2020 - Elsevier
The complexity of cancer biology and its clinical manifestation are driven by genetic,
epigenetic, transcriptomic, proteomic and metabolomic alterations, supported by genomic …

Advances of long noncoding RNAs-mediated regulation in reproduction

KS Liu, TP Li, H Ton, XD Mao, YJ Chen - Chinese Medical Journal, 2018 - mednexus.org
Objective: Advances in genomics and molecular biology have led to the discovery of a large
group of uncharacterized long noncoding RNAs (lncRNAs). Emerging evidence indicated …

Atlas of RNA sequencing profiles for normal human tissues

M Suntsova, N Gaifullin, D Allina, A Reshetun, X Li… - Scientific data, 2019 - nature.com
Comprehensive analysis of molecular pathology requires a collection of reference samples
representing normal tissues from healthy donors. For the available limited collections of …

Multiomics analysis of tumor microenvironment reveals Gata2 and miRNA-124-3p as potential novel biomarkers in ovarian cancer

E Gov, M Kori, KY Arga - Omics: a journal of integrative biology, 2017 - liebertpub.com
Ovarian cancer is a common and, yet, one of the most deadly human cancers due to its
insidious onset and the current lack of robust early diagnostic tests. Tumors are complex …

Immune cell-specific and common molecular signatures in rheumatoid arthritis through molecular network approaches

B Comertpay, E Gov - Biosystems, 2023 - Elsevier
Rheumatoid arthritis (RA) is an autoimmune disorder and common symptom of RA is chronic
synovial inflammation. The pathogenesis of RA is not fully understood. Therefore, we aimed …

Ovarian cancer‐specific dysregulated genes with prognostic significance: scRNA‐Seq with bulk RNA‐Seq data and experimental validation

C Liu, Y Zhang, X Li, D Wang - … of the New York Academy of …, 2022 - Wiley Online Library
A major cause of gynecological cancer‐related deaths worldwide, ovarian cancer is
characterized by heterogeneity in both tumor cells and the tumor microenvironment (TME) …

Femtomolar determination of an ovarian cancer biomarker (miR-200a) in blood plasma using a label free electrochemical biosensor based on L-cysteine …

M Moazampour, HR Zare, Z Shekari - Analytical Methods, 2021 - pubs.rsc.org
In the present study, a label-free electrochemical genosensor was designed based on ZnS
quantum dots functionalized with L-cysteine (Cys–ZnS-QDs) to detect miR-200a, as a …

GD2 and GD3 gangliosides as diagnostic biomarkers for all stages and subtypes of epithelial ovarian cancer

A Galan, A Papaluca, A Nejatie, E Matanes… - Frontiers in …, 2023 - frontiersin.org
Background Ovarian cancer (OC) is the deadliest gynecological cancer, often diagnosed at
advanced stages. A fast and accurate diagnostic method for early-stage OC is needed. The …

[HTML][HTML] Regulatory role of long non-coding RNAs during reproductive disease

K Liu, X Mao, Y Chen, T Li, H Ton - American journal of …, 2018 - ncbi.nlm.nih.gov
Long non-coding RNA (lncRNA) is a group of RNAs with broad biogenesis, which are longer
than 200 nt and highly conserved in their secondary and tertiary structures. lncRNA that …

Application of single cell sequencing technology in ovarian cancer research

Q Yuan, N Lv, Q Chen, S Shen, Y Wang… - Functional & Integrative …, 2024 - Springer
Ovarian cancer is a malignant tumor of ovary. It has the characteristics of difficult early
diagnosis, poor late curative effect and high recurrence rate. It is the biggest disease that …