Structure-activity relationships (SAR) of triazine derivatives: Promising antimicrobial agents

H Liu, S Long, KP Rakesh, GF Zha - European journal of medicinal …, 2020 - Elsevier
The emergence of drug resistance has created unmet medical need for the development of
new classes of antibiotics. Innovation of new antibacterial agents with new mode of action …

1, 2, 3-Triazine scaffold as a potent biologically active moiety: a mini review

R Kumar, A Deep Singh, J Singh… - Mini reviews in …, 2014 - ingentaconnect.com
1, 2, 3-Triazine is an interesting class of heterocyclic compounds. Various synthetic analogs
of 1, 2, 3-triazine have been prepared and evaluated for many pharmacological activities in …

Novel cycloalkylthiophene–imine derivatives bearing benzothiazole scaffold: Synthesis, characterization and antiviral activity evaluation

S Ke, Y Wei, Z Yang, K Wang, Y Liang, L Shi - Bioorganic & medicinal …, 2013 - Elsevier
A series of novel cycloalkylthiophene–imine derivatives containing benzothiazole unit were
designed, synthesized and evaluated for their anti-viral activities. The bio-evaluation results …

Pharmacophore modeling, 3D‐QSAR, synthesis, and anti‐lung cancer evaluation of novel thieno[2,3‐d][1,2,3]triazines targeting EGFR

R Elrayess, YM Abdel Aziz, MS Elgawish… - Archiv der …, 2020 - Wiley Online Library
Abstract Two series of thieno [2, 3‐d][1, 2, 3] triazine derivatives were designed, synthesized,
and biologically evaluated as potential epidermal growth factor receptor (EGFR) inhibitors …

Synthesis and antitumor activities of 1, 2, 3-triazines and their benzo-and heterofused derivatives

S Cascioferro, B Parrino, V Spano, A Carbone… - European Journal of …, 2017 - Elsevier
Triazines are a class of biologically active compounds that exhibit a broad spectrum of
activities, including antibacterial, antifungal, antiviral, antiproliferative, analgesic and anti …

[PDF][PDF] 1, 2, 3-Benzotriazin-4 (3H)-ones: Synthesis, reactions and applications

Z Khalid, HA Ahmad, MA Munawar, M Khan, S Gul - Heterocycles, 2017 - researchgate.net
1,2,3-BENZOTRIAZIN-4(3H)-ONES: SYNTHESIS, REACTIONS AND APPLICATIONS Zunera
Khalid, Hafiz Adnan Ahmad, Munawar Ali Munawar,* Mis Page 1 HETEROCYCLES, Vol. 94 …

Synthesis and docking studies of some 1, 2, 3‐benzotriazine‐4‐one derivatives as potential anticancer agents

AA Fadda, E Abdel‐Latif, A Fekri… - Journal of Heterocyclic …, 2019 - Wiley Online Library
Newly synthesized 1, 2, 3‐benzotriazine‐4‐one derivatives substituted at position‐3 were
characterized by various analytical and spectral techniques. The in vitro antitumor activity …

The antagonistic activity of H1 receptor antagonists as medicinal foods

S Zhou, G Huang, G Chen - Trends in Food Science & Technology, 2020 - Elsevier
At present, there are many kinds of H 1 receptor antagonists as medicinal foods in clinical
application, which can be divided into ethylenediamine antagonist, aminoether antagonist …

Triazine based chemical entities for anticancer activity

JK Gangasani, S Yarasi, VGM Naidu… - Physical Sciences …, 2023 - degruyter.com
Triazine is a six-membered aromatic nitrogen heterocyclic moiety that was extensively
investigated because of its biological properties and, in particular anticancer potentials …

Synthesis and cytotoxicity of novel thiophene, pyran and pyridine derivatives

WW Wardakhan, EM Samir, EE El-Arab - Bulletin of the Chemical Society of …, 2018 - ajol.info
Abstract The reaction of 2-amino-3-cyano-tetrahydrobenzothiophene 3 with ethyl
acetoacetate gave the amide derivatives 5. The reactivity of 5 toward a variety of chemical …