[HTML][HTML] In Vivo Approaches to Understand Arrhythmogenic Cardiomyopathy: Perspectives on Animal Models

G Risato, R Brañas Casas, M Cason, M Bueno Marinas… - Cells, 2024 - mdpi.com
Arrhythmogenic cardiomyopathy (AC) is a hereditary cardiac disorder characterized by the
gradual replacement of cardiomyocytes with fibrous and adipose tissue, leading to …

Targeting Canonical Wnt-signaling Through GSK-3β in Arrhythmogenic Cardiomyopathy: Conservative or Progressive?

BSH Low, A Asimaki - Journal of Cardiovascular Translational Research, 2024 - Springer
Arrhythmogenic cardiomyopathy is a primary myocardial disease and a major cause of
sudden death in all populations of the world. Canonical Wnt signalling is a critical pathway …

PDE3A and GSK3B as Atrial Fibrillation Susceptibility Genes in the Chinese Population via Bioinformatics and Genome-Wide Association Analysis

Z Zhou, Y Wang, X Li, Y Zhang, L Yuan, D Chen… - Biomedicines, 2023 - mdpi.com
Background: Atrial fibrillation (AF) is the most common cardiac arrhythmia, with uncovered
genetic etiology and pathogenesis. We aimed to screen out AF susceptibility genes with …

Notch Interaction with Glycogen Synthase Kinase-3β in Neurodegenerative Disease

T Traub - 2024 - dspace.cuni.cz
Glycogen synthase kinase-3βeta (GSK-3β) is a serine/threonine protein kinase involved in a
number of signaling processes. Pharmacological inhibition of GSK-3β has been shown to …

Signaling mechanisms in the regulation of cardiomyocyte cohesion in arrhythmogenic cardiomyopathy

M Shoykhet - 2023 - edoc.ub.uni-muenchen.de
The heart, being “the engine of life” provides the organism with blood and thereby with
oxygen. Therefore, it is of utmost importance that the human heart can beat correctly and at a …