Impairment of insulin action and metabolic dysregulation have traditionally been associated
with schizophrenia, although the molecular basis of such association remains still elusive …

Diabetic kidney disease (DKD) is the major reason of chronic kidney disease (CKD)-caused
end-stage renal failure (ESRF), and leads to high mortality worldwide. At present, the …

Lung cancer is the most commonly diagnosed cancer worldwide and it is also the most
leading cause of cancer-related deaths. Although multiple generations of targeted …

Diabetes increases the likelihood of developing depression and vice versa. Research on
this bidirectional association has somewhat managed to delineate the interplay among …

Depression has huge social risks of high incidence, disability, and suicide. Its prevalence
and harm in people with hyperglycemia are 2–3 times higher than in normal people …

Dietary interventions for people suffering from major depressive disorder (MDD) are an
ongoing field of research. In this article, we present a comprehensive background for …

The idea that insulin could influence emotional behaviours has long been suggested.
However, the underlying mechanisms have yet to be solved and there is no direct and clear …

Metabolic syndrome is an aggregation of conditions and associated with an increased risk of
developing diabetes, obesity and cardiovascular diseases (CVD). Edible mushrooms are …

In Alzheimer's disease (AD), β-amyloid (Aβ) protein toxicity increases the formation of
reactive oxygen species (ROS) and intracellular calcium levels, resulting in neuronal …

Glutamate is a neurotransmitter that can cause excitatory neurotoxicity when its extracellular
concentration is too high, leading to disrupted calcium balance and increased production of …