Biological functions and analytical strategies of sialic acids in tumor

X Zhou, G Yang, F Guan - Cells, 2020 - mdpi.com
Sialic acids, a subset of nine carbon acidic sugars, often exist as the terminal sugars of
glycans on either glycoproteins or glycolipids on the cell surface. Sialic acids play important …

Recent advances in analytical approaches for glycan and glycopeptide quantitation

DG Delafield, L Li - Molecular & Cellular Proteomics, 2021 - ASBMB
Growing implications of glycosylation in physiological occurrences and human disease have
prompted intensive focus on revealing glycomic perturbations through absolute and relative …

Dual-functional Ti (IV)-IMAC material enables simultaneous enrichment and separation of diverse glycopeptides and phosphopeptides

J Huang, X Liu, D Wang, Y Cui, X Shi, J Dong… - Analytical …, 2021 - ACS Publications
Simultaneous enrichment and fractionation of diverse proteins/peptides possessing different
post-translational modifications (PTMs) from the same biological samples is highly desirable …

Advances in mass spectrometry‐based glycomics—An update covering the period 2017–2021

KB Donohoo, J Wang, M Goli, A Yu, W Peng… - …, 2022 - Wiley Online Library
The wide variety of chemical properties and biological functions found in proteins is attained
via post‐translational modifications like glycosylation. Covalently bonded to proteins …

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2019–2020

DJ Harvey - Mass Spectrometry Reviews, 2023 - Wiley Online Library
This review is the tenth update of the original article published in 1999 on the application of
matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry to the analysis of …

Quantitative Analysis and Structural Elucidation of Fatty Acids by Isobaric Multiplex Labeling Reagents for Carbonyl-Containing Compound (SUGAR) Tags and m …

Y Feng, Y Lv, TJ Gu, B Chen, L Li - Analytical chemistry, 2022 - ACS Publications
In this study, a novel analytical method was developed to investigate fatty acids (FAs) for
relative quantification, carbon–carbon double-bond localization, and cis-/trans-geometry …

6-Plex mdSUGAR Isobaric-Labeling Guide Fingerprint Embedding for Glycomics Analysis

M Ma, M Li, Y Zhu, Y Zhao, F Wu, Z Wang… - Analytical …, 2023 - ACS Publications
Glycans are vital biomolecules with diverse functions in biological processes. Mass
spectrometry (MS) has become the most widely employed technology for glycomics studies …

High-throughput quantitative glycomics enabled by 12-plex isobaric multiplex labeling reagents for carbonyl-containing compound (SUGAR) tags

M Li, Y Feng, M Ma, A Kapur… - Journal of proteome …, 2023 - ACS Publications
Glycans, which are widely distributed on most proteins and cell surfaces, are a class of
important biomolecules playing crucial roles in various biological processes such as …

Multifunctional proximity labeling strategy for lipid raft-specific sialic acid tracking and engineering

Y Guo, P Wang, L Jiang, C Deng, L Zheng… - Bioconjugate …, 2023 - ACS Publications
Lipid raft-specific glycosylation has been implicated in many biological processes, including
intracellular trafficking, cell adhesion, signal transduction, and host–pathogen interactions …

Isomeric Separation of α2, 3/α2, 6-Linked 2-Aminobenzamide (2AB)-Labeled Sialoglycopeptides by C18-LC-MS/MS

P Jiang, Y Huang, CD Gutierrez Reyes… - Analytical …, 2023 - ACS Publications
Determination of the relative expression levels of the α2, 3/α2, 6-sialic acid linkage isomers
on glycoproteins is critical to the analysis of various human diseases such as cancer …