Eosinophils play a homeostatic role in the body's immune responses. These cells are
involved in combating some parasitic, bacterial, and viral infections and certain cancers and …

Despite being the second least represented granulocyte subpopulation in the circulating
blood, eosinophils are receiving a growing interest from the scientific community, due to their …

Eosinophils have been traditionally perceived as terminally differentiated cytotoxic effector
cells. Recent studies have profoundly altered this simplistic view of eosinophils and their …

Experimental and clinical data strongly support a role for the eosinophil in the pathogenesis
of asthma, allergic and parasitic diseases, and hypereosinophilic syndromes, in addition to …

The vertebrate immune system has evolved in concert with a broad range of infectious
agents, including ubiquitous helminth (worm) parasites. The constant pressure of helminth …

Eosinophils derive from the bone marrow and circulate at low levels in the blood in healthy
individuals. These granulated cells preferentially leave the circulation and marginate to …

Eosinophilia is a central feature of the host response to helminth infection. Larval stages of
parasitic worms are killed in vitro by eosinophils in the presence of specific antibodies or …

The functions ascribed to eosinophils have classically been limited to host defence against
certain parasitic infections and potentially deleterious effects in the setting of specific …

Abstract First described by Paul Ehrlich in 1879, who noted its characteristic staining by
acidophilic dyes, for many years, the eosinophil was considered to be an end-effector cell …

Discussions of eosinophils are often descriptions of end‐stage effector cells with destructive
capabilities mediated predominantly by released cytotoxic cationic granule proteins …