Potential role of polycyclic aromatic hydrocarbons as mediators of cardiovascular effects from combustion particles

JA Holme, BC Brinchmann, M Refsnes, M Låg… - Environmental …, 2019 - Springer
Air pollution is the most important environmental risk factor for disease and premature death,
and exposure to combustion particles from vehicles is a major contributor. Human …

[HTML][HTML] A review of food contaminant 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin and its toxicity associated with metabolic disorders

J Gao, Y Xu, T Zhong, X Yu, L Wang, Y Xiao… - Current Research in …, 2023 - Elsevier
Dioxins are a group of chemicals not only regarded as highly toxic trace environmental
contaminants, but also considered typical contaminants in food. Dioxins spread across the …

[HTML][HTML] Additive cardiotoxicity of a bisphenol mixture in zebrafish embryos: The involvement of calcium channel and pump

S Arrokhman, YH Luo, P Lin - Ecotoxicology and Environmental Safety, 2023 - Elsevier
Bisphenol A (BPA) and its analogs, such as bisphenol F (BPF), bisphenol AF (BPAF), and
bisphenol B (BPB), are often simultaneously detected in environmental and human …

PCB 126 induces monocyte/macrophage polarization and inflammation through AhR and NF-κB pathways

C Wang, MC Petriello, B Zhu, B Hennig - Toxicology and applied …, 2019 - Elsevier
Polychlorinated biphenyls (PCBs) are persistent organic pollutants that contribute to
inflammatory diseases such as atherosclerosis, and macrophages play a key role in the …

Boron Compounds Mitigate 2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin-Induced Toxicity in Human Peripheral Blood Mononuclear Cells

ME Arslan, C Baba, OO Tozlu - Toxics, 2024 - mdpi.com
2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin (TCDD) stands as one of the most potent halogenated
polycyclic hydrocarbons, known to inflict substantial cytotoxic effects on both animal and …

Treatment with Ginkgo biloba supplement modulates oxidative disturbances, inflammation and vascular functions in oxygen deprived hypothyroid mice: Involvement …

OG Adebayo, W Aduema, AV Iwueke… - Journal of Food …, 2022 - Wiley Online Library
A double‐hit biological alteration involving exposure to oxygen deprivation in hypothyroid
condition may exacerbate cellular oxidative and inflammatory disturbances comparative to a …

Knock-down of aryl hydrocarbon receptor (AhR) affects the lncRNA-mediated response of porcine granulosa cells (AVG-16 cell line) to 2, 3, 7, 8-tetrachlorodibenzo-p …

S Swigonska, A Nynca, T Molcan, M Jablonska… - Animal Reproduction …, 2023 - Elsevier
Abstract Recently, we found that 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD)–the most
toxic dioxin–affected multiple cellular processes in AhR-knocked-down granulosa cells …

Therapeutic agents with AHR inhibiting and NRF2 activating activity for managing chloracne

M Furue, Y Fuyuno, C Mitoma, H Uchi, G Tsuji - Antioxidants, 2018 - mdpi.com
Chloracne is the major skin symptom caused by dioxin intoxication. Dioxin activates the aryl
hydrocarbon receptor (AHR)–cytochrome p450 1A1 (CYP1A1) system, generates oxidative …

Star-PAP controlled alternative polyadenylation coupled poly (A) tail length regulates protein expression in hypertrophic heart

AP Sudheesh, N Mohan, N Francis… - Nucleic Acids …, 2019 - academic.oup.com
Abstract Alternative polyadenylation (APA)-mediated 3′-untranslated region (UTR)
shortening is known to increase protein expression due to the loss of miRNA regulatory …

Exploring the adverse effects of 1, 3, 6, 8-tetrabromo-9H-carbazole in atherosclerotic model mice by metabolomic profiling integrated with mechanism studies in vitro

T Xu, Y Jiang, H Fu, G Yang, X Hu, Y Chen, Q Zhang… - Chemosphere, 2024 - Elsevier
Given its wide distribution in the environment and latent toxic effects, 1, 3, 6, 8-tetrabromo-
9H-carbazole (1368-BCZ) is an emerging concern that has gained increasing attention …