Acinetobacter baumannii subunit vaccines: recent progress and challenges
YT Lau, HS Tan - Critical reviews in microbiology, 2024 - Taylor & Francis
Acinetobacter baumannii is a Gram-negative, opportunistic pathogen that causes
nosocomial infection with a high mortality rate in immunocompromised individuals. With the …
nosocomial infection with a high mortality rate in immunocompromised individuals. With the …
Vaccine development for bacterial pathogens: Advances, challenges and prospects
IE Mba, HC Sharndama… - Tropical Medicine & …, 2023 - Wiley Online Library
The advent and use of antimicrobials have played a key role in treating potentially life‐
threatening infectious diseases, improving health, and saving the lives of millions of people …
threatening infectious diseases, improving health, and saving the lives of millions of people …
A novel mRNA multi-epitope vaccine of Acinetobacter baumannii based on multi-target protein design in immunoinformatic approach
Y Xu, F Zhu, Z Zhou, S Ma, P Zhang, C Tan, Y Luo… - BMC genomics, 2024 - Springer
Acinetobacter baumannii is a gram-negative bacillus prevalent in nature, capable of thriving
under various environmental conditions. As an opportunistic pathogen, it frequently causes …
under various environmental conditions. As an opportunistic pathogen, it frequently causes …
Increased ompW and ompA expression and higher virulence of Acinetobacter baumannii persister cells
BL Schmitt, BF Leal, M Leyser, MP de Barros… - BMC microbiology, 2023 - Springer
Background Acinetobacter baumannii is one of the main causes of healthcare-associated
infections that threaten public health, and carbapenems, such as meropenem, have been a …
infections that threaten public health, and carbapenems, such as meropenem, have been a …
Promising Acinetobacter baumannii Vaccine Candidates and Drug Targets in Recent Years
In parallel to the uncontrolled use of antibiotics, the emergence of multidrug-resistant
bacteria, like Acinetobacter baumannii, has posed a severe threat. A. baumannii …
bacteria, like Acinetobacter baumannii, has posed a severe threat. A. baumannii …
K. pneumoniae ghosts serve as a novel vaccine formulation to enhance immune responses of A. baumannii subunit vaccine in mice
Z Zhu, Z Zhou, T Zhu, G Kong, Y Yin, G Li, H Jiao - Microbial Pathogenesis, 2024 - Elsevier
Acinetobacter baumannii (A. baumannii) is a prominent nosocomial pathogen, posing a
significant threat to public health. Urgent efforts are required to develop a safe and effective …
significant threat to public health. Urgent efforts are required to develop a safe and effective …
Current treatment strategies for targeting virulence factors and biofilm formation in Acinetobacter baumannii
SL Rajangam, MK Narasimhan - Future Microbiology, 2024 - Taylor & Francis
A higher prevalence of Acinetobacter baumannii infections and mortality rate has been
reported recently in hospital-acquired infections (HAI). The biofilm-forming capability of A …
reported recently in hospital-acquired infections (HAI). The biofilm-forming capability of A …
Serum Level of Antibodies Against Novel Acinetobacter Baumannii OmpA-selected Peptides in ICU Staff: Promise for the Future of Vaccine Development
Extensively drug-resistant Acinetobacter baumannii is considered one of the most
dangerous threats to global health, requiring novel therapeutic interventions. The outer …
dangerous threats to global health, requiring novel therapeutic interventions. The outer …