Light sheet fluorescence microscopy (LSFM) uses a thin sheet of light to excite only
fluorophores within the focal volume. Light sheet microscopes (LSMs) have a true optical …

Histological analysis of biological tissues by mechanical sectioning is significantly time‐
consuming and error‐prone due to loss of important information during sample slicing. In the …

Structured illumination microscopy (SIM) doubles the spatial resolution of a fluorescence
microscope without requiring high laser powers or specialized fluorophores. However, the …

Brain cells are arranged in laminar, nuclear, or columnar structures, spanning a range of
scales. Here, we construct a reliable cell census in the frontal lobe of human cerebral cortex …

Compressed sensing (CS) is a signal processing approach that solves ill-posed inverse
problems, from under-sampled data with respect to the Nyquist criterium. CS exploits …

The light propagation in the medium normally experiences diffraction, dispersion, and
scattering. Studying the light propagation is a century-old problem as the photons may …

Examination of whole organs with subcellular resolution in health, disease, and during
development is necessary to decipher their biological complexity. However, until recently …

Optical contrasts in microscopy are sensitive to light polarization, whose interaction with
molecular dipoles provides an important lever for probing molecular orientation. Polarization …

Heterogeneity in cell populations is a phenomenon encountered in virtually all biological
systems, in whole tissues and cell cultures and from bacterial to mammalian cells. Moreover …

Light-sheet fluorescent microscopy has become the leading technique for in vivo imaging in
the fields of disease, medicine, and cell biology research. However, designing proper …