Emerging rules for subunit-based, multiantigenic, multistage chemically synthesized vaccines
ME Patarroyo, MA Patarroyo - Accounts of chemical research, 2008 - ACS Publications
Seventeen million people die of transmittable diseases and 2/3 of the world's population
suffer them annually. Malaria, tuberculosis, AIDS, hepatitis, and reemerging and new …
suffer them annually. Malaria, tuberculosis, AIDS, hepatitis, and reemerging and new …
Structural and immunological principles leading to chemically synthesized, multiantigenic, multistage, minimal subunit-based vaccine development
Dedicated to the memory of Professors Henry G. Kunkel and Bruce Merrifield (Rockefeller
University, New York), who introduced us to the fascinating worlds of immunology and …
University, New York), who introduced us to the fascinating worlds of immunology and …
Intimate Molecular Interactions of P. falciparum Merozoite Proteins Involved in Invasion of Red Blood Cells and Their Implications for Vaccine Design
LE Rodriguez, H Curtidor, M Urquiza… - Chemical …, 2008 - ACS Publications
Intimate Molecular Interactions of P. falciparum Merozoite Proteins Involved in Invasion of Red
Blood Cells and Their Implications for Vaccine Design | Chemical Reviews ACS ACS …
Blood Cells and Their Implications for Vaccine Design | Chemical Reviews ACS ACS …
[HTML][HTML] Plasmodium falciparum rhoptry neck protein 4 has conserved regions mediating interactions with receptors on human erythrocytes and hepatocyte membrane
FA Pulido-Quevedo, G Arévalo-Pinzón… - International Journal of …, 2023 - Elsevier
Plasmodium falciparum-related malaria represents a serious worldwide public health
problem due to its high mortality rates. P. falciparum expresses rhoptry neck protein 4 …
problem due to its high mortality rates. P. falciparum expresses rhoptry neck protein 4 …
Gauche+ side-chain orientation as a key factor in the search for an immunogenic peptide mixture leading to a complete fully protective vaccine
A Bermúdez, D Calderon, A Moreno-Vranich… - Vaccine, 2014 - Elsevier
Topological and stereo-electron characteristics are essential in major histocompability class
II–peptide–T–cell receptor (MHC–p–TCR) complex formation for inducing an appropriate …
II–peptide–T–cell receptor (MHC–p–TCR) complex formation for inducing an appropriate …
Shifting the polarity of some critical residues in malarial peptides' binding to host cells is a key factor in breaking conserved antigens' code of silence
G Cifuentes, A Bermudez, R Rodriguez… - Medicinal …, 2008 - ingentaconnect.com
As microbes use many mechanisms for avoiding immunological pressure, new strategies
must be developed to bypass the immunological code of silence of conserved, functionally …
must be developed to bypass the immunological code of silence of conserved, functionally …
[HTML][HTML] A rational strategy for a malarial vaccine development
JM Lozano, ME Patarroyo - Microbes and infection, 2007 - Elsevier
Twenty years ago we reported the first synthetic peptide-based anti-malarial vaccine named
SPf66, which conferred limited protective efficacy in large-scale human field-trials. Our …
SPf66, which conferred limited protective efficacy in large-scale human field-trials. Our …
Sequences of the Plasmodium falciparum cytoadherence-linked asexual protein 9 implicated in malaria parasite invasion to erythrocytes
In this study, we synthesized the complete sequence of the CLAG-9 protein as 67 20-mer-
long non-overlapped peptides and assessed their ability to bind to erythrocytes in receptor …
long non-overlapped peptides and assessed their ability to bind to erythrocytes in receptor …
Determinación y caracterización de las regiones de unión de PfRON4 a eritrocitos y hepatocitos humanos
FA Pulido Quevedo - repositorio.unal.edu.co
Plasmodium falciparum durante su ciclo de vida, expresa una amplia gama de proteínas
entre las que se destaca la proteína del cuello de las roptrias 4 (PfRON4). Este es un …
entre las que se destaca la proteína del cuello de las roptrias 4 (PfRON4). Este es un …