According to Genome Sequencing Project statistics (http://www. ncbi. nlm. nih.
gov/genomes/static/gpstat. html), as of February 16, 2012, complete gene sequences have …

The quantification of differences between two or more physiological states of a biological
system is among the most important but also most challenging technical tasks in proteomics …

Extracellular vesicles are emerging as a potent mechanism of intercellular communication
because they can systemically exchange genetic and protein material between cells …

Electrons feed into the mitochondrial electron transport chain (mETC) from NAD-or FAD-
dependent enzymes. A shift from glucose to fatty acids increases electron flux through FAD …

Over the past decade, a series of experimental strategies for mass spectrometry based
quantitative proteomics and corresponding computational methodology for the processing of …

The structural elucidation of small molecules using mass spectrometry plays an important
role in modern life sciences and bioanalytical approaches. This review covers different soft …

The evolution of mass spectrometry–based proteomic technologies has advanced our
understanding of the complex and dynamic nature of proteomes while concurrently …

Heavy metals that are harmful to humans include arsenic, cadmium, chromium, lead,
mercury, and nickel. Some metals or their related compounds may even cause cancer …

LC-MS-based quantitative proteomics has become increasingly applied to a wide range of
biological applications due to growing capabilities for broad proteome coverage and good …

The combination of stable isotope labeling (SIL) with mass spectrometry (MS) allows
comparison of the abundance of thousands of proteins in complex mixtures. However …