Innate immune receptors in platelets and platelet-leukocyte interactions

PRB Dib, AC Quirino-Teixeira, LB Merij… - Journal of Leucocyte …, 2020 - academic.oup.com
Platelets are chief cells in hemostasis. Apart from their hemostatic roles, platelets are major
inflammatory effector cells that can influence both innate and adaptive immune responses …

Platelets in immune response to virus and immunopathology of viral infections

ED Hottz, FA Bozza, PT Bozza - Frontiers in medicine, 2018 - frontiersin.org
Platelets are essential effector cells in hemostasis. Aside from their role in coagulation,
platelets are now recognized as major inflammatory cells with key roles in the innate and …

Cardiovascular disease and thrombosis in HIV infection

MV Perkins, SB Joseph, DP Dittmer… - … , and vascular biology, 2023 - Am Heart Assoc
HIV infection has transitioned from an acute, fatal disease to a chronic one managed by
antiretroviral therapy. Thus, the aging population of people living with HIV (PLWH) continues …

Platelet‐rich plasma: growth factors and pro‐and anti‐inflammatory properties

H El‐Sharkawy, A Kantarci, J Deady… - Journal of …, 2007 - Wiley Online Library
Background: Platelet‐rich plasma (PRP) promotes regeneration of bone, presumably
through the action of concentrated growth factors. However, it is not clear how PRP affects …

Inflammation, immune activation, and cardiovascular disease in HIV

E Nou, J Lo, SK Grinspoon - Aids, 2016 - journals.lww.com
Cardiovascular disease is one of the leading causes of morbidity and mortality in people
living with HIV. Several epidemiological studies have shown an increased risk of myocardial …

Elevated levels of circulating platelet microparticles, VEGF, IL-6 and RANTES in patients with gastric cancer: possible role of a metastasis predictor

HK Kim, KS Song, YS Park, YH Kang, YJ Lee… - European journal of …, 2003 - Elsevier
The activation of coagulation, angiogenesis and inflammatory cytokines are considered to
be related with tumour growth and metastasis. We investigated the plasma levels of platelet …

Host defense role of platelets: engulfment of HIV andStaphylococcus aureus occurs in a specific subcellular compartment and is enhanced by platelet activation

T Youssefian, A Drouin, JM Massé… - Blood, The Journal …, 2002 - ashpublications.org
Platelets can bind and phagocytose infectious microorganisms and so enable their transport
for a prolonged time. To investigate the subcellular events of these interactions, platelets …

Platelet chemokines and chemokine receptors: linking hemostasis, inflammation, and host defense

ARL Gear, D Camerini - Microcirculation, 2003 - Taylor & Francis
Blood platelets play critical roles in hemostasis, providing rapid essential protection against
bleeding and catalyzing the important slower formation of stable blood clots via the …

Enhanced levels of soluble and membrane-bound CD40 ligand in patients with unstable angina: possible reflection of T lymphocyte and platelet involvement in the …

P Aukrust, F Müller, T Ueland, T Berget, E Aaser… - Circulation, 1999 - Am Heart Assoc
Background—The CD40 ligand (CD40L) on activated T cells and platelets may be activating
matrix metalloproteinases, inducing procoagulant activity, and be involved in the …

Immune activation in the course of HIV‐1 infection: causes, phenotypes and persistence under therapy

M Younas, C Psomas, J Reynes, P Corbeau - HIV medicine, 2016 - Wiley Online Library
Systemic immune activation is a striking consequence of HIV‐1 infection. Even in
virologically suppressed patients, some hyperactivity of the immune system and even of the …