Z He, X Dai, W Lyu, M Beaumont… - Molecular Biology and …, 2023 - academic.oup.com
Novel technologies for recovering DNA information from archaeological and historical specimens have made available an ever-increasing amount of temporally spaced genetic …
Resolving the role of natural selection is a basic objective of evolutionary biology. It is generally difficult to detect the influence of selection because ubiquitous non-selective …
Recent advances in DNA sequencing techniques have made it possible to monitor genomes in great detail over time. This improvement provides an opportunity for us to study natural …
Whole-genome time-series allele frequency data are becoming more prevalent as ancient DNA (aDNA) sequences and data from evolve-and-resequence (E&R) experiments are …
Z He, X Dai, W Lyu, M Beaumont… - Molecular Ecology …, 2023 - Wiley Online Library
Innovations in ancient DNA (aDNA) preparation and sequencing technologies have exponentially increased the quality and quantity of aDNA data extracted from ancient …
W Lyu, X Dai, M Beaumont, F Yu… - Molecular Ecology …, 2022 - Wiley Online Library
With the rapid growth of the number of sequenced ancient genomes, there has been increasing interest in using this new information to study past and present adaptation. Such …
Over the past decade there has been an increasing focus on the application of the Wright- Fisher diffusion to the inference of natural selection from genetic time series. A key …
W Lyu, X Dai, M Beaumont, F Yu, Z He - bioRxiv, 2023 - biorxiv.org
Recent technological innovations, such as next generation sequencing and DNA hybridisation enrichment, have made it possible to recover DNA information from historical …
A number of discrete time, finite population size models in genetics describing the dynamics of allele frequencies are known to converge (subject to suitable scaling) to a diffusion …