Modulation of host immunity by helminths: the expanding repertoire of parasite effector molecules

RM Maizels, HH Smits, HJ McSorley - Immunity, 2018 - cell.com
Helminths are extraordinarily successful parasites due to their ability to modulate the host
immune response. They have evolved a spectrum of immunomodulatory molecules that are …

Whipworm and roundworm infections

KJ Else, J Keiser, CV Holland, RK Grencis… - Nature Reviews …, 2020 - nature.com
Trichuriasis and ascariasis are neglected tropical diseases caused by the gastrointestinal
dwelling nematodes Trichuris trichiura (a whipworm) and Ascaris lumbricoides (a …

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif… - autophagy, 2021 - Taylor & Francis
In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

Antiparasitics in animal health: quo vadis?

PM Selzer, C Epe - Trends in parasitology, 2021 - cell.com
Antiparasitics acting on endo-or ectoparasites represent the second largest segment of the
global animal health market, accounting for 23% of market share. However, relatively few …

[HTML][HTML] Heartworm disease–Overview, intervention, and industry perspective

S Noack, J Harrington, DS Carithers… - International Journal for …, 2021 - Elsevier
Dirofilaria immitis, also known as heartworm, is a major parasitic threat for dogs and cats
around the world. Because of its impact on the health and welfare of companion animals …

Schistosomiasis—from immunopathology to vaccines

DP McManus, R Bergquist, P Cai… - Seminars in …, 2020 - Springer
Schistosomiasis (bilharzia) is a neglected tropical disease caused by trematode worms of
the genus Schistosoma. The transmission cycle involves human (or other mammalian) water …

Testing the higher-level phylogenetic classification of Digenea (Platyhelminthes, Trematoda) based on nuclear rDNA sequences before entering the age of the 'next …

GPP De León, DI Hernández-Mena - Journal of Helminthology, 2019 - cambridge.org
Digenea Carus, 1863 represent a highly diverse group of parasitic platyhelminths that infect
all major vertebrate groups as definitive hosts. Morphology is the cornerstone of digenean …

Genomic and transcriptomic variation defines the chromosome-scale assembly of Haemonchus contortus, a model gastrointestinal worm

SR Doyle, A Tracey, R Laing, N Holroyd… - Communications …, 2020 - nature.com
Haemonchus contortus is a globally distributed and economically important gastrointestinal
pathogen of small ruminants and has become a key nematode model for studying …

Biodiversity-based development and evolution: the emerging research systems in model and non-model organisms

L Zhao, F Gao, S Gao, Y Liang, H Long, Z Lv… - Science China Life …, 2021 - Springer
Evolutionary developmental biology, or Evo-Devo for short, has become an established field
that, broadly speaking, seeks to understand how changes in development drive major …

[HTML][HTML] Challenges and opportunities for the adoption of molecular diagnostics for anthelmintic resistance

AC Kotze, JS Gilleard, SR Doyle, RK Prichard - International Journal for …, 2020 - Elsevier
Anthelmintic resistance is a significant threat to livestock production systems worldwide and
is emerging as an important issue in companion animal parasite management. It is also an …