Alzheimer's disease (AD) is one of the neurodegenerative diseases that led to morbidity and
mortality world-wide. It is a complex disease whose etiology is not completely known that …

Indanone is a versatile scaffold that has a number of pharmacological properties. The
successful development and ensuing approval of indanone-derived donepezil as a drug of …

The novel hybrids bearing 4-aminopyridine (4-AP) tethered with substituted 1, 3, 4-
oxadiazole nucleus were designed, synthesized, and evaluated for their potential AChE …

Tyrosinase is a key enzyme responsible for melanin biosynthesis and is effective in
protecting skin damage caused by ultraviolet radiation. As part of ongoing efforts to discover …

Dihydro-5, 6-dimethoxy-2-[4-(4-alkyl-4-methylpiperazinium-1-yl) benzylidine]-1H-inden-1-
one halide salt derivatives as a novel donepezil hybrid analogs with the property of …

Alzheimer's disease (AD) is a neurological disease that disturbs the memory, thinking skills,
and behavior of the affected person. AD is a complex disease caused by the breakdown of …

Fifteen chalcone derivatives 3a–3o were synthesized, and evaluated as multifunctional
agents against Alzheimer's disease. In vitro studies revealed that these compounds inhibited …

Alzheimer's disease is one of the leading causes of disability and death in the global
scenario. Acetylcholinesterase inhibitors are symptomatically involved in the therapeutic …

Inspired by the structures of donepezil and rivastigmine, a novel series of indanone–
carbamate hybrids was synthesized using the pharmacophore hybridization‐based design …

Kitagawia praeruptora (Dunn) Pimenov, commonly known as Qianhu in China, is a widely
used folk Chinese herbal medicine. This article reviews its botanical traits …