Antibiotic resistance is one of the major challenges facing modern medicine worldwide. The
past few decades have witnessed rapid progress in our understanding of the multiple factors …

The last few decades have led to an explosion in our understanding of the major roles that
small regulatory RNAs (sRNAs) play in regulatory circuits and the responses to stress in …

The human body is constantly exposed to microorganisms, which entails manifold
interactions between human cells and diverse commensal or pathogenic bacteria. The …

Bacterial and eukaryotic nuclear RNA polymerases (RNAPs) cap RNA with the oxidized and
reduced forms of the metabolic effector nicotinamide adenine dinucleotide, NAD+ and …

RNAs are often modified to invoke new activities. While many modifications are limited in
frequency, restricted to non-coding RNAs, or present only in select organisms, 5 …

Methylation is a prevalent post-transcriptional modification encountered in coding and non-
coding RNA. For RNA methylation, cells use methyltransferases and small organic …

RNA modifications immensely expand the diversity of the transcriptome, thereby influencing
the function, localization, and stability of RNA. One prominent example of an RNA …

Only recently has it been recognized that the transcriptome of bacteria and archaea can be
spatiotemporally regulated. All types of prokaryotic transcripts—rRNAs, tRNAs, mRNAs, and …

Bacteria possess elaborate systems to manage reactive oxygen and nitrogen species (ROS)
arising from exposure to the mammalian immune system and environmental stresses. Here …

Key message RNA modifications and editing changes constitute 'epitranscriptome'and are
crucial in regulating the development and stress response in plants. Exploration of the …