Adult mesenchymal stem cells (MSCs) represent a subject of intense experimental and
biomedical interest. Recently, trophic activities of MSCs have become the topic of a number …

Background: Under the transcriptional control of numerous factors and intracellular signals,
mesenchymal stem cells (MSCs) can differentiate into various cell types, including …

Bone remodeling is balanced by bone formation and bone resorption as well as by
alterations in the quantities and functions of seed cells, leading to either the maintenance or …

The rebuilding of the normal functioning of the damaged human body bone tissue is one of
the main objectives of bone tissue engineering (BTE). Fabricated scaffolds are mostly …

Osteoporosis, femoral head necrosis, and congenital bone defects are orthopedic disorders
characterized by reduced bone generation and insufficient bone mass. Bone regenerative …

Icariin (ICA) is a pharmacologically active flavonoid glycoside that shows promise in the
treatment and prevention of osteoporosis (OP). However, the mechanisms underlying the …

Osteoporosis is a major public health issue that is expected to rise as the global population
ages. Resveratrol (RES) is a plant polyphenol with various anti-aging properties. RES …

Abstract Bone morphogenetic protein-2 (BMP-2) is a growth factor used to stimulate bone
regeneration in clinical applications. However, there are contradicting reports on the …

Tissue engineering of human fetal osteoblast cells was investigated on gelatin‐
hydroxyapatite (HA), crosslinked, electrospun oriented fiber scaffolds at the different HA …

The natural polyphenol Resveratrol (RSV) claims numerous positive effects on health due to
the well documented biological effects demonstrating its potential as a disease-preventing …