Distinct profiles of autoantibodies directed to intracellular antigens can be detected in the
systemic connective tissue diseases. They aid in establishing the correct diagnosis and are …

The antiphospholipid syndrome (APS) is defined by the presence of anti-phospholipid
antibodies (aPLs) and venous or arterial thrombosis, recurrent pregnancy loss, or …

Anti-phospholipid (aPL) antibodies that exhibit binding in cardiolipin (CL) ELISA can be
purified to greater than 95% purity by sequential phospholipid affinity and ion-exchange …

The binding of affinity-purified anticardiolipin antibodies (ACA) to liposomes that contained
cardiolipin or phosphatidylserine was investigated. ACA bound to these liposomes only in …

▪ Objective: To determine the clinical course and influence of antithrombotic therapy in
patients with lupus anticoagulant or anticardiolipin antibodies, or both, after the first …

Plasmas from 16 patients that were found to be positive both for anticardiolipin antibodies
(ACA) and lupus anticoagulants (LA) were incubated with liposomes that contained anionic …

Publisher Summary There are two major methods for detecting Antiphospholipid (aPL)
antibodies. The first is based on a solid-phase immunoassay employing purified …

Anticardiolipin antibodies (aCL) derived from the sera of individuals exhibiting the
antiphospholipid syndrome (APS) directly bind to beta 2-glycoprotein I (beta 2-GPI), which is …

BACKGROUND Heparan sulphates play key roles in conception and early pregnancy
events. The role of heparin, a structural analogue, and its application to assisted conception …

Adsorption of serum proteins to the liposomal surface plays a critical role in the clearance of
liposomes from the blood circulation. In this review, we will discuss the role of the liposomal …