Advances in aptamer-based nuclear imaging

W Song, Y Song, Q Li, C Fan, X Lan, D Jiang - European Journal of …, 2022 - Springer
Aptamers are short oligonucleotides that bind to specific target molecules. They have been
extensively explored in biomedical applications, including biosensing, medical imaging, and …

Intraoperative fluorescence molecular imaging accelerates the coming of precision surgery in China

Z Zhang, K He, C Chi, Z Hu, J Tian - European Journal of Nuclear Medicine …, 2022 - Springer
Purpose China has the largest cancer population globally. Surgery is the main choice for
most solid cancer patients. Intraoperative fluorescence molecular imaging (FMI) has shown …

Supervised machine learning enables non-invasive lesion characterization in primary prostate cancer with [68Ga]Ga-PSMA-11 PET/MRI

L Papp, CP Spielvogel, B Grubmüller… - European journal of …, 2021 - Springer
Purpose Risk classification of primary prostate cancer in clinical routine is mainly based on
prostate-specific antigen (PSA) levels, Gleason scores from biopsy samples, and tumor …

Novel multiparametric magnetic resonance imaging-based deep learning and clinical parameter integration for the prediction of long-term biochemical recurrence-free …

HW Lee, E Kim, I Na, CK Kim, SI Seo, H Park - Cancers, 2023 - mdpi.com
Simple Summary Existing research on predicting biochemical recurrence after prostate
surgery has been insufficient. Here, we aimed to predict biochemical recurrence after radical …

68Ga-PSMA PET/CT combined with PET/ultrasound-guided prostate biopsy can diagnose clinically significant prostate cancer in men with previous negative biopsy …

C Liu, T Liu, Z Zhang, N Zhang, P Du… - Journal of Nuclear …, 2020 - Soc Nuclear Med
The purpose of this study was to investigate the feasibility and diagnostic efficacy of 68Ga-
prostate-specific membrane antigen (PSMA) PET/CT combined with PET/ultrasound-guided …

Diagnostic performance of 68Ga-PSMA PET/CT in the detection of prostate cancer prior to initial biopsy: comparison with cancer-predicting nomograms

J Zhang, S Shao, P Wu, D Liu, B Yang, D Han… - European Journal of …, 2019 - Springer
Purpose To assess the diagnostic performance of 68 Ga-PSMA PET/CT for detecting
suspected prostate cancer (PCa) and to compare it with that of two cancer-predicting …

Preclinical evaluation and pilot clinical study of Al18F-PSMA-BCH for prostate cancer PET imaging

T Liu, C Liu, X Xu, F Liu, X Guo, N Li… - Journal of Nuclear …, 2019 - Soc Nuclear Med
Prostate-specific membrane antigen (PSMA)–targeted radioligands have played an
important role in the diagnosis of prostate cancer. In this study, we developed an Al18F …

H3nota Derivatives Possessing Picolyl and Picolinate Pendants for Ga3+ Coordination and 67Ga3+ Radiolabeling

A Marlin, A Koller, E Madarasi, M Cordier… - Inorganic …, 2023 - ACS Publications
We synthesized, thanks to the regiospecific N-functionalization using an orthoamide
intermediate, two 1, 4, 7-triazacyclononane derivatives containing an acetate arm and either …

Radiosynthesis and preclinical evaluation of bispecific PSMA/FAP heterodimers for tumor imaging

K Hu, L Li, Y Huang, S Ye, J Zhong, Q Yan, Y Zhong… - Pharmaceuticals, 2022 - mdpi.com
Due to tumor heterogeneity and complex tumor–stromal interactions in multicellular systems,
the efficiency of monospecific tracers for tumor diagnosis and therapy is currently limited. In …

Up-to-date imaging and diagnostic techniques for prostate cancer: A literature review

M Zhu, Z Liang, T Feng, Z Mai, S Jin, L Wu, H Zhou… - Diagnostics, 2023 - mdpi.com
Prostate cancer (PCa) faces great challenges in early diagnosis, which often leads not only
to unnecessary, invasive procedures, but to over-diagnosis and treatment as well, thus …