Nucleic acid vaccines are a method of immunization aiming to elicit immune responses akin
to live attenuated vaccines. In this method, DNA or messenger RNA (mRNA) sequences are …

In the last half-century, the development of biodegradable polymeric materials for
biomedical applications has advanced significantly. Biodegradable polymeric materials are …

Pancreatic tumors are highly desmoplastic and immunosuppressive. Delivery and
distribution of drugs within pancreatic tumors are compromised due to intrinsic physical and …

Utilization of polymers as biomaterials has greatly impacted the advancement of modern
medicine. Specifically, polymeric biomaterials that are biodegradable provide the significant …

Scaffolds play a crucial role in tissue engineering. Biodegradable polymers with great
processing flexibility are the predominant scaffolding materials. Synthetic biodegradable …

Annually, swine influenza A virus (SwIAV) causes severe economic loss to swine industry.
Currently used inactivated SwIAV vaccines administered by intramuscular injection provide …

For humans, companion animals, and food producing animals, vaccination has been touted
as the most successful medical intervention for the prevention of disease in the twentieth …

Targeting pathogen recognition receptors on dendritic cells (DCs) offers the advantage of
triggering specific signaling pathways to induce a tailored and robust immune response. In …

Despite the successes provided by vaccination, many challenges still exist with respect to
controlling new and re-emerging infectious diseases. Innovative vaccine platforms …

Techniques in materials design, immunophenotyping, and informatics can be valuable tools
for using a molecular based approach to design vaccine adjuvants capable of inducing …