Altered metabolism of lipids is currently considered a hallmark characteristic of many
malignancies, including colorectal cancer (CRC). Lipids are a large group of metabolites …

Cancer causes considerable morbidity and mortality across the world. Socioeconomic,
environmental, and lifestyle factors contribute to the increasing cancer prevalence …

Mosaic loss of chromosome Y (LOY) in circulating white blood cells is the most common
form of clonal mosaicism,,,–, yet our knowledge of the causes and consequences of this is …

Rationale: Evidence linking saturated fat intake with cardiovascular health is controversial.
The associations of unsaturated fats with total and cardiovascular disease (CVD) mortality …

Background We aimed to map and describe the current state of Mendelian randomization
(MR) literature on cancer risk and to identify associations supported by robust evidence …

Simple Summary Colorectal cancer (CRC) is the third-most diagnosed cancer and the
second-leading cause of cancer-related deaths worldwide. Limitations in early and accurate …

Background Higher adiposity increases the risk of colorectal cancer (CRC), but whether this
relationship varies by anatomical sub-site or by sex is unclear. Further, the metabolic …

Background: Increasingly, studies have discovered that different fatty acids (Fas) are linked
to colorectal cancer (CRC) risk. Methods: We systematically searched Embase and Medline …

Cancer is one of the leading global causes of death in both men and women. Colorectal
cancer (CRC) alone accounts for∼ 10% of total new global cases and poses an over 4 …

Objective To summarize the associations between potential causal factors and colorectal
cancer (CRC) risk based on existing Mendelian randomization studies. Methods This …