Cigarette smoking is the leading cause of preventable disease and death in the United
States. Cardiovascular comorbidities associated with both active and secondhand cigarette …

Abstract Arginase (EC 3.5. 3.1) is the bimanganese enzyme that converts L‐arginine into
ornithine and urea. This enzyme was discovered more than a century ago and early α …

Nitric oxide (NO) is one of the most important molecules released by endothelial cells, and
its antiatherogenic properties support cardiovascular homeostasis. Diminished NO …

Background Endothelial dysfunction and arterial stiffening play major roles in cardiovascular
diseases. The critical role for the miR-181 family in vascular inflammation has been …

Objective—Arginase 2 (Arg2) is a critical target in atherosclerosis because it controls
endothelial nitric oxide, proliferation, fibrosis, and inflammation. Regulators of Arg2 …

Existing US epidemiological data demonstrate that consumption of smokeless tobacco,
particularly moist snuff, is less harmful than cigarette smoking. However, the molecular and …

Purpose miR-190a-5p expression alters dynamically in response to hypoxia. However, the
role of miR-190a-5p expression in hypoxia-induced pulmonary hypertension (PH) remains …

Background The identification of large‐artery stiffness as a major, independent risk factor for
cardiovascular disease–associated morbidity and death has focused attention on identifying …

We investigated the effects of methanol extract of Artocarpus altilis (AA) on atherogenic
indices and redox status of cellular system of rats fed with dietary cholesterol while Questran …

Arginase is a metalloenzyme which hydrolyzes L‐arginine to L‐ornithine and urea. Since its
discovery, in the early 1900s, this enzyme has gained increasing attention, as literature …