The actin cytoskeleton, a network of protein-polymers, is responsible for the mechanical stability of cells. This biopolymer network is also crucial for processes that require spatial …
Most theories of soft matter elasticity assume that the local strain in a sample after deformation is identical everywhere and equal to the macroscopic strain, or equivalently that …
K Nagy-Smith, E Moore… - Proceedings of the …, 2015 - National Acad Sciences
Most, if not all, peptide-and protein-based hydrogels formed by self-assembly can be characterized as kinetically trapped 3D networks of fibrils. The propensity of disease …
The actin cytoskeleton is organized into diverse meshworks and bundles that support many aspects of cell physiology. Understanding the self-assembly of these actin-based structures …
KM Schmoller, P Fernandez, RC Arevalo… - Nature …, 2010 - nature.com
Nonlinear deformations can irreversibly alter the mechanical properties of materials. Most soft materials, such as rubber and living tissues, display pronounced softening when …
The high diversity of cytoskeletal actin structures is accomplished by myriads of actin binding proteins (ABPs). Depending on its concentration, even a single type of ABP can induce …
KW Müller, RF Bruinsma, O Lieleg, AR Bausch… - Physical review …, 2014 - APS
We present a theoretical and computational analysis of the rheology of networks made up of bundles of semiflexible filaments bound by transient cross-linkers. Such systems are …
In living cells, lipid membranes and biopolymers determine each other's conformation in a delicate force balance. Cellular polymers such as actin filaments are strongly confined by …
Living systems provide a paradigmatic example of active soft matter. Cells and tissues comprise viscoelastic materials that exert forces and can actively change shape. This …