Combination therapy of radiation and hyperthermia, focusing on the synergistic anti-cancer effects and research trends

S Kwon, S Jung, SH Baek - Antioxidants, 2023 - mdpi.com
Despite significant therapeutic advances, the toxicity of conventional therapies remains a
major obstacle to their application. Radiation therapy (RT) is an important component of …

Combined hyperthermia and radiotherapy for prostate cancer: a systematic review

J Le Guevelou, ME Chirila, V Achard… - International Journal …, 2022 - Taylor & Francis
Optimization of treatment strategies for prostate cancer patients treated with curative
radiation therapy (RT) represents one of the major challenges for the radiation oncologist …

3D tumour spheroids for the prediction of the effects of radiation and hyperthermia treatments

SC Brüningk, I Rivens, C Box, U Oelfke, G Ter Haar - Scientific Reports, 2020 - nature.com
For multimodality therapies such as the combination of hyperthermia and radiation,
quantification of biological effects is key for dose prescription and response prediction …

[HTML][HTML] Enhancement radiation-induced apoptosis in C6 glioma tumor-bearing rats via pH-responsive magnetic graphene oxide nanocarrier

S Shirvalilou, S Khoei, S Khoee, SR Mahdavi… - … of Photochemistry and …, 2020 - Elsevier
iodo-2-deoxyuridine (IUdR) has been demonstrated to induce an appreciable
radiosensitizing effect on glioblastoma patients, but due to the short circulation half-life times …

Physical and biological properties of 5-fluorouracil polymer-coated magnetite nanographene oxide as a new thermosensitizer for alternative magnetic hyperthermia …

L Kiamohammadi, L Asadi, S Shirvalilou, S Khoei… - ACS …, 2021 - ACS Publications
This study reports a new procedure for utilizing 5-fluorouracil (5-Fu)-loaded
polycaprolactone (PCL)/chitosan-covered magnetite nanographene oxide (5 …

Dual-drug delivery by thermo-responsive Janus nanogel for improved cellular uptake, sustained release, and combination chemo-thermal therapy

S Shirvalilou, S Khoei, S Khoee, M Soleymani… - International Journal of …, 2024 - Elsevier
The goal of this work was to examine the heat-sensitizing effects of Janus-coated magnetic
nanoparticles (JMNPs) as a vehicle for 5-fluorouracil (5-Fu) and Quercetin (Qu) in C6 and …

Cytotoxic effect of 5-fluorouracil-loaded polymer-coated magnetite nanographene oxide combined with radiofrequency

L Asadi, S Shirvalilou, S Khoee… - Anti-Cancer Agents in …, 2018 - ingentaconnect.com
Background: Despite the development of conventional therapies including surgery,
radiotherapy, chemotherapy and hyperthermia, the prognosis remains very poor. Recently …

Salinomycin and IR780-loaded upconversion nanoparticles influence biological behavior of liver cancer stem cells by persistently activating the MAPK signaling …

B Zhang, Z Ding, X Wen, G Song, Q Luo - Experimental Cell Research, 2024 - Elsevier
The combination of chemotherapy and phototherapy has emerged as a promising
therapeutic approach for enhancing the efficacy of cancer treatment and mitigating drug …

Let's Go 3D! New Generation of Models for Evaluating Drug Response and Resistance in Prostate Cancer

T Petrić, M Sabol - International Journal of Molecular Sciences, 2023 - mdpi.com
Prostate cancer (PC) is the third most frequently diagnosed cancer worldwide and the
second most frequent in men. Several risk factors can contribute to the development of PC …

A novel framework for the optimization of simultaneous ThermoBrachyTherapy

I Androulakis, RMC Mestrom, MEMC Christianen… - Cancers, 2022 - mdpi.com
Simple Summary ThermoBrachyTherapy, a combination therapy where radiation and heat
are simultaneously applied using needle-shaped applicators from within the target, is a …