malERA: an updated research agenda for malaria elimination and eradication
Achieving a malaria-free world presents exciting scientific challenges as well as
overwhelming health, equity, and economic benefits. WHO and countries are setting …
overwhelming health, equity, and economic benefits. WHO and countries are setting …
Genetic diversity and deletion of Plasmodium falciparum histidine-rich protein 2 and 3: a threat to diagnosis of P. falciparum malaria
Background PfHRP2-based rapid diagnostic tests (RDTs), based on the recognition of the
Plasmodium falciparum histidine-rich protein 2, are currently the most used tests in malaria …
Plasmodium falciparum histidine-rich protein 2, are currently the most used tests in malaria …
Prevalence of pfhrp2 and/or pfhrp3 Gene Deletion in Plasmodium falciparum Population in Eight Highly Endemic States in India
PK Bharti, HS Chandel, A Ahmad, S Krishna… - PloS one, 2016 - journals.plos.org
Background Plasmodium falciparum encoded histidine rich protein (HRP2) based malaria
rapid diagnostic tests (RDTs) are used in India. Deletion of pfhrp2 and pfhrp3 genes …
rapid diagnostic tests (RDTs) are used in India. Deletion of pfhrp2 and pfhrp3 genes …
Factors affecting the performance of HRP2-based malaria rapid diagnostic tests
The recent COVID-19 pandemic has profoundly impacted global malaria elimination
programs, resulting in a sharp increase in malaria morbidity and mortality. To reduce this …
programs, resulting in a sharp increase in malaria morbidity and mortality. To reduce this …
Deletion of Plasmodium falciparum Histidine-Rich Protein 2 (pfhrp2) and Histidine-Rich Protein 3 (pfhrp3) Genes in Colombian Parasites
C Murillo Solano, S Akinyi Okoth, JF Abdallah, Z Pava… - PloS one, 2015 - journals.plos.org
A number of studies have analyzed the performance of malaria rapid diagnostic tests (RDTs)
in Colombia with discrepancies in performance being attributed to a combination of factors …
in Colombia with discrepancies in performance being attributed to a combination of factors …
Identification of Plasmodium falciparum isolates lacking histidine-rich protein 2 and 3 in Eritrea
M Menegon, M L'Episcopia, AM Nurahmed… - Infection, Genetics and …, 2017 - Elsevier
The histidine-rich protein 2 of Plasmodium falciparum is the most common malaria antigen
targeted by rapid diagnostic tests for the specific diagnosis of P. falciparum. Recently, pfhrp2 …
targeted by rapid diagnostic tests for the specific diagnosis of P. falciparum. Recently, pfhrp2 …
Bead-based immunoassay allows sub-picogram detection of histidine-rich protein 2 from Plasmodium falciparum and estimates reliability of malaria rapid diagnostic …
E Rogier, M Plucinski, N Lucchi, K Mace, M Chang… - PLoS …, 2017 - journals.plos.org
Detection of histidine-rich protein 2 (HRP2) from the malaria parasite Plasmodium
falciparum provides evidence for active or recent infection, and is utilized for both diagnostic …
falciparum provides evidence for active or recent infection, and is utilized for both diagnostic …
Molecular surveillance of pfhrp2 and pfhrp3 genes deletion in Plasmodium falciparum isolates and the implications for rapid diagnostic tests in Nigeria
Prompt diagnosis and appropriate treatment of malaria remain the hallmark for reducing
malaria-related mortality in high transmission areas. Plasmodium falciparum histidine-rich …
malaria-related mortality in high transmission areas. Plasmodium falciparum histidine-rich …
Impact of Plasmodium falciparum pfhrp2 and pfhrp3 gene deletions on malaria control worldwide: a systematic review and meta-analysis
Background Deletion of pfhrp2 and/or pfhrp3 genes cause false negatives in malaria rapid
diagnostic test (RDT) and threating malaria control strategies. This systematic review aims to …
diagnostic test (RDT) and threating malaria control strategies. This systematic review aims to …
Limitations of rapid diagnostic tests in malaria surveys in areas with varied transmission intensity in Uganda 2017-2019: Implications for selection and use of HRP2 …
AB Bosco, JI Nankabirwa, A Yeka, S Nsobya, K Gresty… - PloS one, 2020 - journals.plos.org
Background Plasmodium falciparum histidine-rich protein 2 (HRP2)-based rapid diagnostic
tests (RDTs) are exclusively recommended for malaria diagnosis in Uganda; however, their …
tests (RDTs) are exclusively recommended for malaria diagnosis in Uganda; however, their …