A review: Pharmacological aspects of metal based 1, 2, 4-triazole derived Schiff bases

W Zafar, SH Sumrra, ZH Chohan - European journal of medicinal chemistry, 2021 - Elsevier
Clinical reports have highlighted the radical increase of antibiotic resistance. As a result,
multidrug resistance has emerged as a serious threat to human health. Many organic …

Ultrasound-assisted green synthesis of triazole-based azomethine/thiazolidin-4-one hybrid inhibitors for cancer therapy through targeting dysregulation signatures of …

AH Abdelmonsef, AM El-Saghier… - Green Chemistry Letters …, 2023 - Taylor & Francis
The overexpression of Rab proteins was linked to cancer development, making this family of
proteins an attractive drug target for the identification of novel inhibitors against tumor …

Novel 2-acetamido-2-ylidene-4-imidazole derivatives (El-Saghier reaction): Green synthesis, biological assessment, and molecular docking

AM El-Saghier, A Abdou, MAA Mohamed… - ACS …, 2023 - ACS Publications
El-Saghier reaction is the novel, general, and green reaction of various amines with ethyl
cyanoacetate and ethyl glycinate hydrochloride. A new series of imidazolidin-4-ones and bis …

Trace minerals in human health: Iron, zinc, copper, manganese and fluorine

CS Silva, C Moutinho, A Ferreira da Vinha… - International Journal of …, 2019 - bdigital.ufp.pt
Trace elements exist in the environment in small amounts but play an essential part in
sustaining various physiological and metabolic processes occurring within living tissues, as …

Metal incorporated aminothiazole-derived compounds: synthesis, density function theory analysis, in vitro antibacterial and antioxidant evaluation

SH Sumrra, Z Arshad, W Zafar… - Royal Society …, 2021 - royalsocietypublishing.org
The present study advocates the combined experimental and computational study of metal-
based aminothiazole-derived Schiff base ligands. The structure and electronic properties of …

Facile synthesis, X-Ray structure of new multi-substituted aryl imidazole ligand, biological screening and DNA binding of its Cr (III), Fe (III) and Cu (II) coordination …

LH Abdel-Rahman, AA Abdelhamid… - Journal of Molecular …, 2020 - Elsevier
A simple highly adjustable and effective synthesis of aryl imidazole ligand HL namely (2-(1-
butyl-4, 5-diphenyl-1H-imidazole-2-yl)(4-bromophenol) was discussed where it was …

DFT, anticancer, antioxidant and molecular docking investigations of some ternary Ni (II) complexes with 2-[(E)-[4-(dimethylamino) phenyl] methyleneamino] phenol

RK Mohapatra, MM El-ajaily, FS Alassbaly, AK Sarangi… - Chemical Papers, 2021 - Springer
The biological activities of some ternary nickel complexes with a Schiff base obtained from 4-
dimethylaminobenzaldehyde and 2-aminophenol have been reported. The Schiff base (HL …

An operationally simple, one‐pot, convenient synthesis, and in vitro anti‐inflammatory activity of some new spirotriazolotriazine derivatives

AM El‐Saghier, SS Enaili, A Abdou… - Journal of …, 2024 - Wiley Online Library
The wide biological actions of triazolotriazine hybrids, benzene‐sulfonamide derivatives,
exhibit a good chance of displaying in vitro anti‐inflammatory effects. An operationally …

New Copper Complex on Fe3O4 Nanoparticles as a Highly Efficient Reusable Nanocatalyst for Synthesis of Polyhydroquinolines in Water

MA Ashraf, Z Liu, WX Peng, C Gao - Catalysis Letters, 2020 - Springer
In this work, we present a simple, environmentally friendly and economical route for the
preparation of a novel copper-Schiff-base organometallic complex on Fe 3 O 4 …

An efficient eco-friendly, simple, and green synthesis of some new spiro-N-(4-sulfamoyl-phenyl)-1, 3, 4-thiadiazole-2-carboxamide derivatives as potential inhibitors of …

AM El-Saghier, SS Enaili, A Abdou, AM Kadry - Molecular Diversity, 2024 - Springer
Introduction The coronavirus disease 2019 (COVID-19) pandemic has caused a global
health crisis. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a …