Hepatocytes were isolated by established procedures from freshly‐excised livers of
ovariectomized rats. Integrity of the cells was verified by DNA, protein, and calcium contents …

In order to assess the subcellular distribution of estrogen-binding components in their native
state, plasma membrane and other cell fractions were prepared by quantitative methods …

Publisher Summary This chapter evaluates the aspects of the individual steps in the staging
of vectorial pathway and assesses their potential metabolic consequences in the processing …

An organic anion-transporting polypeptide that mediates sodi-urn-independent uptake of
negatively charged sulfobrornoph-thalein and bile salts has recently been cloned from rat …

A procedure was developed to isolate plasma membranes from rabbit skeletal muscle. K+-
dependent phosphatase activity was used as marker enzyme for plasma membranes and …

Binding studies with [3H] dexamethasone identified two binding sites on plasma membranes
prepared from the male rat liver, a low-capacity site with a KD of 7.0 nM and a higher …

The postnatal development of the sodium transport mechanism in the rat kidney, as judged
by the activity of renal plasma membrane Na-K-ATPase, was studied. Highly purified kidney …

The metabolism of corticosteroids, especially of aldosterone, the most important
mineralocorticoid, and of prednisone, a synthetic glucocorticoid, was studied in the isolated …

A general hypothesis has been developed in recent years to describe the mechanism of
action of steriod hormones. Circulating steroid, having dissociated from serum carrier …

Aldosterone, as the main mineralocorticoid hormone, plays a pivotal role in the regulation of
sodium and water homeostasis as well as acid-base regulation. In its classical mode of …