The dormant blood microbiome in chronic, inflammatory diseases

M Potgieter, J Bester, DB Kell… - FEMS microbiology …, 2015 - academic.oup.com
Blood in healthy organisms is seen as a 'sterile'environment: it lacks proliferating microbes.
Dormant or not-immediately-culturable forms are not absent, however, as intracellular …

The perfect storm: incarceration and the high-risk environment perpetuating transmission of HIV, hepatitis C virus, and tuberculosis in Eastern Europe and Central Asia

FL Altice, L Azbel, J Stone, E Brooks-Pollock… - The Lancet, 2016 - thelancet.com
Despite global reductions in HIV incidence and mortality, the 15 UNAIDS-designated
countries of Eastern Europe and Central Asia (EECA) that gained independence from the …

Mechanisms underlying hepatitis C virus-associated hepatic fibrosis

M Khatun, RB Ray - Cells, 2019 - mdpi.com
Hepatitis C virus (HCV) infection often causes liver diseases, including fibrosis, cirrhosis and
hepatocellular carcinoma (HCC). Liver fibrosis is the outcome of the wound healing …

Hepatic decompensation in antiretroviral-treated patients co-infected with HIV and hepatitis C virus compared with hepatitis C Virus–monoinfected patients: a cohort …

VL Re III, MJ Kallan, JP Tate, AR Localio… - Annals of internal …, 2014 - acpjournals.org
Background: The incidence and determinants of hepatic decompensation have been
incompletely examined among patients co-infected with HIV and hepatitis C virus (HCV) in …

Mesencephalic astrocyte‐derived Neurotrophic factor inhibits liver cancer through small ubiquitin‐related modifier (SUMO) ylation‐related suppression of NF‐κB/snail …

J Liu, Z Wu, D Han, C Wei, Y Liang, T Jiang, L Chen… - Hepatology, 2020 - journals.lww.com
Conclusions An elevated FLI (≥ 60) is a risk factor for all‐cause mortality in HIV–HCV‐
coinfected patients independently of liver fibrosis and HCV cure. In the present era of nearly …

Oncogenic effects of HIV-1 proteins, mechanisms behind

M Isaguliants, E Bayurova, D Avdoshina… - Cancers, 2021 - mdpi.com
Simple Summary People living with human immunodeficiency virus type 1 (HIV-1)(PLWH)
are at increased risk of developing cancer despite successful antiretroviral therapy (ART) …

A tale of two viruses: immunological insights into HCV/HIV coinfection

ST Gobran, P Ancuta, NH Shoukry - Frontiers in immunology, 2021 - frontiersin.org
Nearly 2.3 million individuals worldwide are coinfected with human immunodeficiency virus
(HIV) and hepatitis C virus (HCV). Odds of HCV infection are six times higher in people living …

[HTML][HTML] Human immunodeficiency virus and hepatotropic viruses co-morbidities as the inducers of liver injury progression

M Ganesan, LY Poluektova… - World journal of …, 2019 - ncbi.nlm.nih.gov
Hepatotropic viruses induced hepatitis progresses much faster and causes more liver-
related health problems in people co-infected with human immunodeficiency virus (HIV) …

Toll-like receptor response to human immunodeficiency virus type 1 or co-infection with hepatitis B or C virus: an overview

MEH Kayesh, M Kohara… - International Journal of …, 2023 - mdpi.com
Toll-like receptors (TLRs) are evolutionarily conserved pattern recognition receptors that
play important roles in the early detection of pathogen-associated molecular patterns and …

HCV induces transforming growth factor β1 through activation of endoplasmic reticulum stress and the unfolded protein response

P Chusri, K Kumthip, J Hong, C Zhu, X Duan, N Jilg… - Scientific reports, 2016 - nature.com
HCV replication disrupts normal endoplasmic reticulum (ER) function and activates a
signaling network called the unfolded protein response (UPR). UPR is directed by three ER …