Importance Whether the improvement in myocardial perfusion provided by percutaneous
coronary intervention (PCI) is associated with symptomatic relief or improved outcomes has …

Objectives: This study sought to examine the clinical performance of and theoretical basis for
the instantaneous wave-free ratio (iFR) approximation to the fractional flow reserve (FFR) …

Objective We propose a novel technique called pressure‐bounded coronary flow reserve
(pb‐CFR) and demonstrate its application to the randomized DEFER trial. Background …

Aims: Fractional flow reserve (FFR) allows accurate investigation of the functional
significance of intermediate coronary stenoses. The present study set out to study the impact …

Background Fractional flow reserve (FFR) is an invasive method to assess the functional
significance of coronary stenoses. The value of FFR in diabetic patients is controversial …

Background: The functional significance of an intermediate coronary lesion is crucial for
determining the treatment strategy, but age-related changes in cardiovascular function could …

Background This study investigated whether the microvascular dysfunction differed between
culprit and non‐culprit vessels in patients with acute coronary syndrome who underwent …

Background Vulnerable plaque features including lipidic plaque have been shown to affect
fractional flow reserve (FFR). Given that formation and propagation of lipid plaque is …

Background Coronary flow reserve (CFR) represents entire coronary compensatory
capacity, while fractional flow reserve (FFR) is a standard to evaluate functional severity of …

Objectives The objective of this study is to evaluate the association between the value of
post-PCI vFFR, Δ vFFR and adverse clinical outcomes, residual angina and quality of life …