Functional hydrogels for the treatment of myocardial infarction

T Wu, W Liu - NPG Asia Materials, 2022 - nature.com
Myocardial infarction (MI) is a major disease posing a significant threat to human health, as it
leads to necrosis of numerous cardiomyocytes (CMs), left ventricle dilation, and cardiac …

Reactive oxygen species (ROS): utilizing injectable antioxidative hydrogels and ROS-producing therapies to manage the double-edged sword

Z He, Q Xu, B Newland, R Foley, I Lara-Sáez… - Journal of Materials …, 2021 - pubs.rsc.org
Reactive oxygen species (ROS) are generated in cellular metabolism and are essential for
cellular signalling networks and physiological functions. However, the functions of ROS are …

Rational design of smart hydrogels for biomedical applications

Y Zhang, Y Huang - Frontiers in Chemistry, 2021 - frontiersin.org
Hydrogels are polymeric three-dimensional network structures with high water content. Due
to their superior biocompatibility and low toxicity, hydrogels play a significant role in the …

Antioxidant Hydrogels: Antioxidant Mechanisms, Design Strategies, and Applications in the Treatment of Oxidative Stress‐Related Diseases

B Hu, Y Ouyang, T Zhao, Z Wang, Q Yan… - Advanced …, 2024 - Wiley Online Library
Oxidative stress is a biochemical process that disrupts the redox balance due to an excess
of oxidized substances within the cell. Oxidative stress is closely associated with a multitude …

A ROS-scavenging hydrogel loaded with bacterial quorum sensing inhibitor hyperbranched poly-L-lysine promotes the wound scar-free healing of infected skin in vivo

H Lu, C Tu, T Zhou, W Zhang, Y Zhan, J Ding… - Chemical Engineering …, 2022 - Elsevier
Staphylococcus aureus (S. aureus) is the most common pathogen causing skin and soft
tissue infections. The emergence and spread of methicillin-resistant S. aureus (MRSA) pose …

Advances in functional hydrogel wound dressings: a review

Z Shen, C Zhang, T Wang, J Xu - Polymers, 2023 - mdpi.com
One of the most advanced, promising, and commercially viable research issues in the world
of hydrogel dressing is gaining functionality to achieve improved therapeutic impact or even …

Reactive oxygen species–degradable polythioketal urethane foam dressings to promote porcine skin wound repair

P Patil, KA Russo, JT McCune, AC Pollins… - Science translational …, 2022 - science.org
Porous, resorbable biomaterials can serve as temporary scaffolds that support cell
infiltration, tissue formation, and remodeling of nonhealing skin wounds. Synthetic …

From the updated landscape of the emerging biologics for IBDs treatment to the new delivery systems

J Yang, D Li, M Zhang, G Lin, S Hu, H Xu - Journal of Controlled Release, 2023 - Elsevier
Inflammatory bowel diseases (IBDs) treatments have shifted from small-molecular
therapeutics to the oncoming biologics. The first-line biologics against the moderate-to …

Nanomaterial-based reactive oxygen species scavengers for osteoarthritis therapy

S Zhang, L Wang, Y Kang, J Wu, Z Zhang - Acta Biomaterialia, 2023 - Elsevier
Reactive oxygen species (ROS) play distinct but important roles in physiological and
pathophysiological processes. Recent studies on osteoarthritis (OA) have suggested that …

[HTML][HTML] Hydrogel degradation promotes angiogenic and regenerative potential of cell spheroids for wound healing

VL Thai, DH Ramos-Rodriguez, M Mesfin, JK Leach - Materials Today Bio, 2023 - Elsevier
Chronic nonhealing wounds are debilitating and diminish one's quality of life, necessitating
the development of improved strategies for effective treatment. Biomaterial-and cell-based …