Asymmetric catalysis mediated by synthetic peptides, version 2.0: expansion of scope and mechanisms

AJ Metrano, AJ Chinn, CR Shugrue, EA Stone… - Chemical …, 2020 - ACS Publications
Low molecular weight synthetic peptides have been demonstrated to be effective catalysts
for an increasingly wide array of asymmetric transformations. In many cases, these peptide …

Asymmetric catalysis by architectural and functional molecular engineering: practical chemo‐and stereoselective hydrogenation of ketones

R Noyori, T Ohkuma - Angewandte Chemie International …, 2001 - Wiley Online Library
Hydrogenation is a core technology in chemical synthesis. High rates and selectivities are
attainable only by the coordination of structurally well‐designed catalysts and suitable …

Catalytic enantioselective Strecker reactions and analogous syntheses

H Gröger - Chemical Reviews, 2003 - ACS Publications
The Strecker reaction which was reported already in 1850 is the oldest known synthesis of R-
amino acids. 1 This reaction comprises a condensation of an aldehyde, ammonia, and …

Rapid determination of enantiomeric excess: a focus on optical approaches

D Leung, SO Kang, EV Anslyn - Chemical Society Reviews, 2012 - pubs.rsc.org
High-throughput screening (HTS) methods are becoming increasingly essential in
discovering chiral catalysts or auxiliaries for asymmetric transformations due to the advent of …

Combinatorial and evolution‐based methods in the creation of enantioselective catalysts

MT Reetz - Angewandte Chemie International Edition, 2001 - Wiley Online Library
Combinatorial methods in the development of enantioselective homogeneous catalysts
constitute a new branch of catalysis research. The goal is to prepare libraries of potential …

Structure and reactivity of “unusual” N-heterocyclic carbene (NHC) palladium complexes synthesized from imidazolium salts

H Lebel, MK Janes, AB Charette… - Journal of the American …, 2004 - ACS Publications
The reaction between palladium acetate and IMES⊙ HCl leads to the formation of a novel
palladium complex. The X-ray crystal structure analysis reveals that the palladium is C (2) …

Combinatorial materials science and catalysis

B Jandeleit, DJ Schaefer, TS Powers… - Angewandte Chemie …, 1999 - Wiley Online Library
After forever changing the drug discovery process in the pharmaceutical industry,
combinatorial chemistry methodologies are increasingly being applied to the discovery and …

Asymmetrische Katalyse mit hinsichtlich Struktur und Funktion gezielt entworfenen Molekülen: die chemo‐und stereoselektive Hydrierung von Ketonen

R Noyori, T Ohkuma - Angewandte Chemie, 2001 - Wiley Online Library
Die Hydrierung ist eines der Schlüsselverfahren der chemischen Synthese. Hohe
Reaktionsgeschwindigkeiten und Selektivitäten sind hierbei lediglich durch die Kombination …

Cationic nickel and palladium complexes with bidentate ligands for the C C linkage of olefins

S Mecking - Coordination Chemistry Reviews, 2000 - Elsevier
Cationic complexes of late transition metals with multidentate ligands have recently been
found to catalyze various novel homo-and copolymerization reactions of olefins. In this …

Combinatorial libraries of chiral ligands for enantioselective catalysis

C Gennari, U Piarulli - Chemical reviews, 2003 - ACS Publications
The discovery of efficient methods for gaining access to enantiomerically pure compounds in
the development of pharmaceuticals, agrochemicals, and flavors has been a substantial …