A review of the biological role of miRNAs in prostate cancer suppression and progression

AS Doghish, A Ismail, HA El-Mahdy, MA Elkady… - International journal of …, 2022 - Elsevier
Prostate cancer (PC) is the third-leading cause of cancer-related deaths worldwide.
Although the current treatment strategies are progressing rapidly, PC is still representing a …

Liquid biopsy in prostate cancer management—Current challenges and future perspectives

F Crocetto, G Russo, E Di Zazzo, P Pisapia, BF Mirto… - Cancers, 2022 - mdpi.com
Simple Summary Prostate cancer (PCa) is a widespread malignancy, representing the
second leading cause of cancer-related death in men. In the last years, liquid biopsy has …

[HTML][HTML] MicroRNAs as clinical tools for diagnosis, prognosis, and therapy in prostate cancer

F Ghamlouche, A Yehya, Y Zeid, H Fakhereddine… - Translational …, 2023 - Elsevier
Prostate cancer (PCa) is one of the most commonly diagnosed cancers among men
worldwide. Despite the presence of accumulated clinical strategies for PCa management …

Downregulation of miR-99b-5p and upregulation of nuclear mTOR cooperatively promotes the tumor aggressiveness and drug resistance in African American prostate …

H Gujrati, S Ha, M Waseem, BD Wang - International Journal of Molecular …, 2022 - mdpi.com
Mammalian target of rapamycin (mTOR) regulates various fundamental cellular events
including cell proliferation, protein synthesis, metabolism, apoptosis, and autophagy. Tumor …

MiR-182 is upregulated in prostate cancer and contributes to tumor progression by targeting MITF

MYC Stafford, DJ McKenna - International Journal of Molecular Sciences, 2023 - mdpi.com
Altered expression of microRNA-182-5p (miR-182) has been consistently linked with many
cancers, but its specific role in prostate cancer remains unclear. In particular, its contribution …

Proteomics, phosphoproteomics and mirna analysis of circulating extracellular vesicles through automated and high-throughput isolation

H Zhang, YH Cai, Y Ding, G Zhang, Y Liu, J Sun… - Cells, 2022 - mdpi.com
Extracellular vesicles (EVs) play an important role in the diagnosis and treatment of
diseases because of their rich molecular contents involved in intercellular communication …

Extracellular circulating miRNAs as potential non-invasive biomarkers in non-small cell lung cancer patients

J Raczkowska, A Bielska, A Krętowski… - Frontiers in …, 2023 - frontiersin.org
Non-small cell lung cancer (NSCLC) comprises 85% of all lung cancers and is a malignant
condition resistant to advanced-stage treatment. Despite the advancement in detection and …

Deregulated microRNAs involved in prostate cancer aggressiveness and treatment resistance mechanisms

H Gujrati, S Ha, BD Wang - Cancers, 2023 - mdpi.com
Simple Summary Accumulating studies have highlighted the critical roles of microRNAs in
tumorigenesis and cancer treatment responses. Here, we systematically review the scientific …

[HTML][HTML] Prostate cancer bone metastases biology and clinical management

E Archer Goode, N Wang… - Oncology Letters, 2023 - spandidos-publications.com
Prostate cancer (PCa) is one of the most prominent causes of cancer‑related mortality in the
male population. A highly impactful prognostic factor for patients diagnosed with PCa is the …

Prostate cancer: Novel genetic and immunologic biomarkers

M Samare-Najaf, H Kouchaki, SM Mahini… - Clinica Chimica …, 2024 - Elsevier
Prostate cancer (PCa) is considered one of the most prevalent male malignancies
worldwide with a global burden estimated to increase over the next two decades. Due to …