Stimulating tear production: spotlight on neurostimulation

MD Yu, JK Park, AL Kossler - Clinical Ophthalmology, 2021 - Taylor & Francis
Dry eye disease (DED) affects up to one-third of the global population. Traditional therapies,
including topical lubricants, have been employed with variable success in the treatment of …

Lacrimal gland insufficiency in aqueous deficiency dry eye disease: recent advances in pathogenesis, diagnosis, and treatment

MB Doctor, S Basu - Seminars in Ophthalmology, 2022 - Taylor & Francis
Background Aqueous deficiency dry eye disease is a chronic and potentially sight-
threatening condition, that occurs due to the dysfunction of the lacrimal glands. The aim of …

[HTML][HTML] Bilateral Effect of OC-01 (Varenicline Solution) nasal spray for treatment of signs and symptoms in individuals with mild, moderate, and severe dry eye disease

J Katz, LM Periman, S Maiti, E Sarnicola, M Hemphill… - Clinical Therapeutics, 2022 - Elsevier
Purpose This study compares outcomes of therapy with OC-01 (varenicline solution) for dry
eye disease in study eyes and nonstudy fellow eyes of participants in 2 pivotal clinical trials …

[HTML][HTML] How Eyelid Changes May Impact on Tears

A Di Zazzo, E Villani, S Barabino… - Journal of Clinical …, 2024 - mdpi.com
This article examines the impact of eyelid margin diseases on tear film composition and
associated ocular surface disorders. It highlights the prevalence of blepharitis and …

Advances in clinical examination of lacrimal gland

Y Lin, Y Zhang, K Shi, H Wu, S Ou - Frontiers in Medicine, 2023 - frontiersin.org
In humans, the lacrimal gland is located in the socket of the frontal bone above the outer
orbital area. As an essential part of the eye surface, the gland is fixed to the orbital …

Effectiveness of intranasal tear neurostimulation for treatment of dry eye disease: A meta-analysis

Z Li, X Wang, X Li - Ophthalmology and therapy, 2023 - Springer
Introduction To assess the effectiveness and safety of intranasal tear neurostimulation in the
treatment of dry eye disease. Methods We performed a meta-analysis of four databases from …

Neurostimulation for tear production

JK Park, S Cremers, AL Kossler - Current Opinion in …, 2019 - journals.lww.com
Neurostimulation for enhanced tear production is a promising new treatment option for DED.
Stimulation of the lacrimal nerve and anterior ethmoid nerve both effectively increase tear …

Retrospective cohort study of self-reported outcomes after unilateral dacryocystorhinostomy in patients with bilateral epiphora and suspected nasolacrimal obstruction

JXL Li, E Slavich, R Sacks, M Coroneo, G Wilcsek - Orbit, 2024 - Taylor & Francis
Purpose This study aimed to quantify the proportion of patients with bilateral epiphora and
suspected nasolacrimal obstruction who self-reported improved epiphora bilaterally …

[HTML][HTML] Zwitterionic poly (carboxybetaine methacrylate)(polyCBMA) decreases desiccating damage to corneal epithelial cells

YC Sun, LL Wu, YA Chang, TY Li, Y Lin, FR Hu… - Colloid and Interface …, 2022 - Elsevier
Dry eye disease (DED) is a common disorder. The first-line treatment typically involves
lubricating eye drops, which, however, are less effective for evaporative DED, implying the …

[HTML][HTML] Современные тенденции лечения синдрома «сухого глаза»

ЕБ Татарникова, ОИ Кривошеина - РМЖ. Клиническая …, 2021 - cyberleninka.ru
В течение уже нескольких лет одним из наиболее распространенных
офтальмологических синдромов, сопровождающихся патологическими изменениями …