The concept of 'lifestyle 'includes different factors such as nutrition, behavior, stress, physical
activity, working habits, smoking and alcohol consumption. Increasing evidence shows that …

Exposure to early life stress (ELS), such as childhood abuse and neglect is a well
established major risk factor for developing psychiatric and behavioral disorders later in life …

Early-life adversity is associated with a broad scope of life-long health and behavioral
disorders. Particularly critical is the role of the mother. A possible mechanism is that these …

Diet and energy metabolism affect gene expression, which influences human health and
disease. Here, we discuss the role of epigenetics as a mechanistic link between energy …

The brain is one of the major target organs of alcohol actions. Alcohol abuse can lead to
alterations in brain structure and functions and, in some cases, to neurodegeneration …

Studying placental functions is crucial for understanding pregnancy complications. However,
imaging placenta is challenging due to its depth, volume, and motion distortions. In this …

Background Prenatal alcohol exposure is the leading preventable cause of behavioral and
cognitive deficits, which may affect between 2 and 5% of children in North America. While …

Through DNA methylation, histone modifications, and small regulatory RNAs the epigenome
systematically controls gene expression during development, both in utero and throughout …

Epigenetics refers to a variety of processes that have heritable effects on gene expression
programs without changes in DNA sequence. Key players in epigenetic control are chemical …

It is well established that the regulation of epigenetic factors, including chromatic
reorganization, histone modifications, DNA methylation, and miRNA regulation, is critical for …