The cytoskeleton of animal cells is one of the most complicated and functionally versatile
structures, involved in processes such as endocytosis, cell division, intra-cellular transport …

Microtubules have a key role in plant morphogenesis, as they control the oriented deposition
of cellulose in the cell wall, and thus growth anisotropy. The idea that mechanical stress …

Eukaryotic cells rely on long-lived microtubules for intracellular transport and as
compression-bearing elements. We considered that long-lived microtubules are acetylated …

Long-lived microtubules endow the eukaryotic cell with long-range transport abilities. While
long-lived microtubules are acetylated on Lys40 of α-tubulin (αK40), acetylation takes place …

Microtubules—which define the shape of axons, cilia and flagella, and provide tracks for
intracellular transport—can be highly bent by intracellular forces, and microtubule structure …

Cells generate diverse microtubule populations by polymerization of a common α/β-tubulin
building block. How microtubule associated proteins translate microtubule heterogeneity …

We use open active contours to quantify cytoskeletal structures imaged by fluorescence
microscopy in two and three dimensions. We developed an interactive software tool for …

The diverse functions of microtubules require stiff structures possessing sufficient lateral
flexibility to enable bending with high curvature. We used cryo-electron microscopy to …

Many cell functions rely on the ability of microtubules to self-organize as complex networks.
In plants, cortical microtubules are essential to determine cell shape as they guide the …

Kinesins drive the transport of cellular cargoes as they walk along microtubule tracks;
however, recent work has suggested that the physical act of kinesins walking along …