The mammalian target of rapamycin (mTOR) is a protein kinase that controls cellular
metabolism, catabolism, immune responses, autophagy, survival, proliferation, and …

Cancer is the second leading cause of human death globally. PI3K/Akt/mTOR signaling is
one of the most frequently dysregulated signaling pathways observed in cancer patients that …

Abstract Phosphatidylinositol 3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR)
signaling pathway is one of the major cellular signaling pathways that plays an important …

Abstract The PI3K-Akt-mechanistic (formerly mammalian) target of the rapamycin (mTOR)
signaling pathway is important in a variety of biological activities, including cellular …

Mechanistic target of rapamycin (mTOR) is a protein kinase regulating cell growth, survival,
metabolism, and immunity. mTOR is usually assembled into several complexes such as …

Mammalian target of rapamycin (mTOR) is a Ser/Thr kinase that regulates a wide range of
functions, including cell growth, proliferation, survival, autophagy, metabolism, and …

The mTOR pathway was discovered in the late 1970s after the compound and natural
inhibitor of mTOR, rapamycin was isolated from the bacterium Streptomyces hygroscopicus …

The Target of Rapamycin (TOR) is a conserved serine/threonine (ser/thr) kinase that
functions in two, distinct, multiprotein complexes called TORC1 and TORC2. Each complex …

Abstract The phosphoinositide 3-kinase (PI3K)/Akt/mechanistic target of rapamycin (mTOR)
signaling network is a master regulator of processes that contribute to tumorigenesis and …

Despite significant improvement in the management of atherosclerosis, this slowly
progressing disease continues to affect countless patients around the world. Recently, the …